2001 NIH Postdoctoral Job Fair

PanVera Corporation

Company Description: PanVera Corporation, a subsidiary of Vertex Pharmaceuticals, is turning genetic information from the Human Genome Project into tools for drug discovery. The company, established in 1992 in Madison, Wisconsin is an international leader in the development of products and technologies that allow pharmaceutical companies to select and develop new drugs more rapidly and cost-effectively.

Position Descriptions: Senior Director, Commercial Development

Responsibilities for this position include: develop long-range plans, strategies and tactics for areas of responsibility; establish business and contractual relationships with leading drug discovery instrumentation companies to leverage the sale of PanVera reagents and assays into their markets; negotiate and manage the establishment of “Large, Key Account” global contracts with Pharmaceutical and Biotech companies; manage the OEM sales and business opportunities; negotiate and manage contracting with distribution channels globally; coordinate with research, marketing and sales personnel to ensure consistency and complimentary of initiatives and decisions. Qualifications for applying candidates: minimum of 10 years sales experience in the life sciences or biopharmaceutical market; experience planning, initiating, negotiating and successfully closing large contacts in the Life Sciences research or biopharmaceutical industry; familiarity with Life Sciences research market Dist!

ribution Channels; positive industry reputation for professionalism, fairness and interpersonal relationship building; previous management experience; minimum BS degree, advanced business or science degree preferred.

Director, Human Resources

The person in this position will be expected to be a strategic partner with the management team in planning, staffing and developing PanVera's rapidly growing workforce. While managing the basic administrative tasks will be necessary, this person will contribute most by helping senior management strategically build a strong and sustainable workforce. Responsibilities of this position include: overall HR policy and procedures (regulatory compliance); general HR administration (compensation, benefits, performance management, new employee training/orientation, etc.); HR planning; organizational staffing (recruiting) and development; performance management; succession planning; employee relations proponent. Qualifications include: HR Degree or formal training preferred; minimum 7 years management and 10 years HR experience; demonstrated success in managing an HR department; familiarity with HR regulations; strength in Organizational Development. The person in this position will !

also be upbeat and outgoing, with a friendly personality. He or she will work well with an established senior management team, be non-bureaucratic (comfortable in a fast pace, entrepreneurial environment). This person will have a "can-do" attitude (management team will need basic support).

Territory Manager, Massachusetts/Connecticut

PanVera has an immediate opening for a Territory Manager (TM). TM’s sell PanVera’s proprietary products, focusing on drug metabolizing enzymes, proteins and HTS assays to pharmaceutical/drug discovery companies on a direct-sales basis (70% of focus). TM’s also sell our Life Science products direct and manage dealer sales reps as an extension of our direct sales force in the Life Science market (30% of focus). Specific duties and responsibilities include: qualify and follow-up on leads generated from trade show activity, web hits, targeted mail lists; conduct sales visits and presentations; establish and advance key account relationships; analyze sales data for new and extraordinary purchases and opportunities for repeat orders; gather new product and service ideas focusing specifically on enhancing our understanding of new technologies and trends in drug discovery; collect market intelligence, competitive benchmarks, customer expectations, trends, and opportunities in drug d!

iscovery; utilize sales automation tools to enhance efficiency and internal and external communication. Candidates will possess: broad based knowledge of the drug discovery and life science markets; proven ability to effectively communicate with key contacts at all levels within pharmaceutical and biotech organizations; ability to champion and successfully manage customer relationships; ideal candidate will hold a BS/MS in molecular biology, biochemistry, or related discipline and several years in pharmaceutical research, and 3+ years of drug discovery sales experience preferred. The ideal candidate will also be in the top 20% of sales performance in your current organization for the last two years; have prior experience with Goldmine, ACT or another CRM application; be willing to travel overnight 10% of the time.

Territory Manager, Pennsylvania/New Jersey

Development Scientist, Fermentation (Bacterial Fermentation & Recombinant Protein Expression)

This position offers the opportunity to work in an exciting environment on the expression of drug target proteins for high throughput screening and structural studies by PanVera’s pharmaceutical customers. In addition, the qualified candidate will be expected to contribute to the development of innovative multiplex approaches for increasing throughput in bacterial expression optimization and production methods. Responsibilities include: doing production and development fermentation runs for expression of recombinant proteins in controlled fermentors; maintaining fermentation lab equipment; contributing toward process improvements for optimal expression of soluble eukaryotic proteins; performing standard biochemical assays (e.g. protein & DNA concentration determinations) and characterization techniques (e.g. gel electrophoresis & immunoblots); maintain a laboratory notebook in good order; participation in multidiscipline, group development projects. A qualified candidate wil!

l have: associate Degree/BS/MS/PhD in Microbiology or relevant field; good working knowledge of the techniques used to optimize expression of functional eukaryotic proteins in E. coli; experience operating controlled fermentors is essential; experience with downstream processing and protein purification would also be helpful; ability to work as a member of a team.

Senior Scientist, Contract Services (Protein Manufacturing)

Specific duties of this position include: use of basic laboratory skills in Biochemistry or a related field to purify recombinant proteins using traditional chromotography and automated methods, clone DNA among recombinant vectors, or assay enzymatic or molecular binding events with a variety of techniques including radioactivity tracer and fluorescence methods; experience with standard biochemical assays (e.g. protein & DNA concentration determinations) and characterization techniques (e.g. gel electrophoresis & immunoblots); maintain a laboratory notebook in good order; participation in multidiscipline, group development projects. Qualified applicants will: have a PhD in Chemistry, Biochemistry or a relevant field and 2-5 years experience in a biotechnology setting; be capable of working completely independently on multiple projects simultaneously from inception through completion or delivery; have independence in experimental design, data analysis, and problem solving; be!

adaptable and self-motivated; have the ability to work under time constraints and respond quickly in a fast-paced, growing environment; have excellent written skills and the ability to work as a member of a team.

Protein Development Scientist

This role involves the expression, purification, and characterization of recombinant proteins. This position will report to the manager of Contract Manufacturing and will participate in the development and manufacture of protein based products. Successful candidates will perform expression, purification, and assaying of recombinant proteins in Bacterial and Mammalian systems. The ideal candidate will possess BS/MS in Biochemistry or related relevant field including ≥ 4 years demonstrated work experience in protein expression and purification. Individuals should be self-motivated, adaptable, independent, and possess excellent written and verbal communication skills. Experience with large-scale purification and/or molecular biology techniques is highly desired.

Cell Culture Scientist

PanVera has an immediate opening for a Cell Culture Scientist to work in the eukaryotic culture facility. The ideal candidate would have a B.S./M.S. in biochemistry or a related field. Specific duties include: maintenance of cell stocks, transfections, viral titering, optimization of recombinant protein expression, and design of large production runs. This person will be able to interact with other scientists in multidisciplinary projects by is expected to work independently. The ideal candidate will have 1-3 years of experience working with mammalian or insect cell (baculovirus) cultures, should be self-motivated, have the ability to work cooperatively in the lab, and maintain a laboratory notebook in good order.

Lab Assistant (Part-time)

The person in this position will be responsible for keeping the laboratory stocked with clean glassware and preparing the laboratory’s reagents. Specific duties include: collecting dirty lab glassware and cleaning according to PanVera’s standard methods; sterilizing (autoclave) specific glassware for cell culture applications, common laboratory consumables, including pipet tips, glassware, and plasticware; preparation of common buffer solutions, media broths, and media agars; routine checks and log entries on freezer/refrigerator temperatures, safety equipment, water quality, etc.; general lab neatness, including laboratory trash collection; additional responsibilities possible, including laboratory work. Qualifications for this position include: basic Chemistry coursework, with an understanding of solution preparation; High School degree or equivalent; Associate degree or B.S. preferred, college students welcome to apply; no previous experience is necessary, but laboratory ! exposure a plus; good computational skills; good multi-tasking and time management skills; ability to work under time constraints and with changing priorities; time commitment of 15-20 hours per week.

Shipping/Receiving Representative

The Shipping/Receiving Representative will be responsible for shipping and receiving functions at PanVera. Primary duties are picking, packing and readying shipments to customer; kit packaging; and receiving and distributing goods. Qualifications include: three years experience working in a warehouse capacity with perishable products; business computer experience and understanding of inventory management; ability to lift and transport up to sixty pounds; and have good eyesight and manual dexterity for computer and mouse work.