Staff Scientist I

The Clinical and Investigative Orthopaedics Surgery (CIOS) Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), is recruiting for a Staff Scientist position. The successful candidate is expected to have demonstrated significant expertise in bone biology, mouse models, osteoblast biology and genetic analysis in support of NIAMS clinical investigations. The ideal candidate will also possess strong interpersonal skills and relevant career experiences to interface with a wide range of audiences, ranging from Senior Investigator to postdoctoral fellow to postbaccalaureate students. He/She will also possess excellent analytical and writing skills, strong organizational skills and the ability to prioritize complex tasks. He/She will have strong computer skills and experience with iPS cells and deep knowledge of osteoblast biology is essential. He/She will perform a variety of specialized laboratory techniques in support of the sections long-term investigations into the rare bone disease melorheostosis. Techniques include stem cell cultures, osteoblast differentiation assays, CRISPR techniques and mouse modeling. These skills will be needed to develop an experimental strategy to determine the functional consequences of somatic mutations that lead to hyperostosis seen in melorhreostosis. Expertise in T cells, B cells, and other relevant immune populations using animal or human samples, in support of the scientific research program will be required. He/She will also be responsible for the development, design and implementation of new analysis techniques needed to answer research questions. It is expected that the candidate will maintain detailed records of laboratory experiments, perform statistical analysis of data, prepare tables, charts, graphs, summaries, and other materials for inclusion in publications. He/She will contribute as an author and/or co-author in the writing and preparation of scientific papers for publication, present new research data in group settings, at meetings or seminars.

Applicants should have a doctoral degree in cell biology or a related field and at least eight years of postdoctoral experience. A record of peer-reviewed publications is required. The successful candidate should have strong communication skills and the ability to work collaboratively.