Postdoctoral Fellow - Pathophysiology
National Institute of Child Health and Human Development, Bethesda, MD and surrounding area
About the position
The Rouault laboratory at the National Institutes of Health is recruiting one or more Postdoctoral Fellows for fully funded research to study areas including the pathophysiology of neurodegeneration, mitochondrial diseases, coronaviral infection and dyserythropoiesis as these conditions relate to pathologies of iron metabolism and biogenesis of iron sulfur cofactors.
Our laboratory combines biochemical, cell biological and mouse modeling approaches to understand diseases that develop because of abnormalities in iron metabolism, or that depend on normal iron sulfur cluster biogenesis. We are interested in understanding the pathophysiology of axonal degeneration in specific disease contexts using microfluidic techniques. We are also interested in pursuing our recent discoveries that SARS-CoV-2 host-derived iron sulfur cofactors are required for replication, and in extending our discoveries to related viral diseases. We seek to develop therapies for genetic and viral diseases based on insights into underlying molecular pathogenesis.
We are located within a highly collaborative network of outstanding labs in the Porter Neuroscience Research Center and the NIH Intramural Program, providing a stimulating and collegial interdisciplinary training environment. The candidate will be able to apply cutting edge imaging (e.g. 2-photon, EM, light sheet), next generation sequencing (10X platforms), proteomics (mass spectrometry) bioinformatics (Biowulf computing cluster), flow cytometry and ICP-MS for their studies.
Apply for this vacancy
What you'll need to apply
Interested individuals should email a cover letter, copy of their Curriculum vitae, and names and contact details of three referees to:
Tracey Rouault, M.D.
Distinguished NIH Investigator
Head, Section on Human Iron Metabolism
Molecular Medicine Branch, DIR, NICHD
Please write “Postdoctoral Application 2023” in the subject header. Applications will be accepted until the position is filled.
Candidates may be U.S. citizens, resident aliens, or nonresident aliens and should have a Ph.D. with a strong track-record of peer-reviewed publications, and less than 4 years of postdoctoral experience.
Basic expertise in biochemistry, molecular and cellular biology is essential, and expertise in relevant techniques ranging from advanced imaging to relevant specialized chemistry techniques will be a positive. We strongly encourage individuals from diverse backgrounds to apply. The position(s) is fully funded. However, there are ample opportunities for fellowship grant-writing, and other career development support is readily available.
The position is subject to a background investigation.
The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.