Job
Postdoctoral Fellowship - Stalled Replication Repair Group
Organization
National Institute of Environmental Health Sciences, Research Triangle Park, NC
Scientific focus area
Cancer Biology, Structural Biology, Chromosome Biology, Genetics and Genomics, Molecular Biology and Biochemistry
Dr. Rajula Elango Alleva’s lab at the Genome Integrity & Structural Biology Laboratory (GISBL) at the National Institute of Environmental Health Sciences (NIEHS) has one open postdoctoral position available in Spring 2025. The lab will work on defining the rules that govern the processing, repair, and restart of stalled/broken mammalian replication forks and determine the contributions of various DNA repair pathways to genomic integrity.
About the position
The stalled replication repair group will use mammalian cells (mouse embryonic stem cells) to explore the genetic requirements of a recently identified novel role for the Fanconi anemia (FA) pathway in the repair of a deleterious DNA lesion, DNA-protein crosslinks (DPCs) (Elango et al., NSMB, 2022). We will do this by using various cutting-edge techniques including CRISPR/Cas9 mediated gene-engineering and high-throughput sequencing techniques. These studies will allow us to exploit one or multiple steps of this repair pathway as a promising new target for therapy.
Apply for this vacancy
What you'll need to apply
Curriculum vitae with bibliography (if applicable) One-page statement of research interests Names and contact information of three references
Contact name
Dr. Rajula Elango Alleva
Contact email
Qualifications
Postdoctoral candidates must have a Ph.D. degree in Biological Sciences or a related discipline within the last 5 years, with a strong background in genetics and molecular biology. The candidates must have strong communications skills, both oral and written, and have peer-reviewed publications in reputable journals
Disclaimer/Fine Print
Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. The NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities.
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