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Scientist: Molecular Engineering, Structure-Function

Adicet Bio, Redwood City, California

Position Description:

Adicet Bio is seeking motivated individuals to advance gamma delta CAR-T development by working at the interface of antibody discovery and cell therapy development. The ideal candidate will be creative, think outside the box, excited to learn, and enjoy working in a collaborative environment that provides huge growth potential.

Key Responsibilities:

  • Work collaboratively with teams across the Research department on new target development projects in immuno-oncology
  • Development/optimization/execution of extensive immune cell-based assays for in vitro functional studies, including T cell-based screening of CAR candidates
  • Development/optimization/execution of cell-based assays to investigate CAR structure-activity relationships involving engineering and/or functional screening of CAR domains such as hinges and costimulatory domains
  • Data generation, data analysis, and communication to immediate team and cross-functional teams

Qualifications:

  • BS, MS/MSc or PhD in Biology, Biochemistry, Immunology and related disciplines
  • 3+ years of relevant academic and/or industry experience
  • Broad technical expertise working with antibodies and cell therapies
  • Hands-on tissue culture experience is required (maintaining cell lines, handling primary cells, freezing and thawing cells is required)
  • Experience with cell-based assays such as T cell proliferation, activation, in vitro cytotoxicity assays
  • Hands-on experience with multi-color flow cytometry; experience with phosphoflow is a plus
  • Hands-on experience with fluorescence and luminescence-based readouts using a plate reader
  • Experience with automation of assays to increase throughput is a plus
  • Ability to delve into literature to drive assay development
  • Ability to multitask and meet deadlines in a fast-paced environment
  • Excellent verbal and written communication skills
  • Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

Benefits: 

  • Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

To Apply:

Please visit this webpage and search for "Scientist: Molecular Engineering, Structure-Function" to apply for the position: https://www.adicetbio.com/careers/openings/

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.