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Staff Scientist - High-Throughput Genetics

National Human Genome Research Institute, Bethesda, Maryland

Position Description:

The National Human Genome Research Institute (NHGRI), within the National Institutes of Health (NIH), is seeking exceptional candidates for a Staff Scientist position. The position is in the Systems Biology and Genome Engineering Section (SBGE) of NHGRI’s Intramural Research Program. SBGE’s focus is on genome functionalization: understanding how genetic differences across the genome affect phenotypes. To tackle this question, researchers in SBGE develop and apply new high-throughput genetic methods. This includes harnessing the strengths of CRISPR, large scale oligo synthesis, and yeast genetics. Using these techniques, the staff scientist will be leading a project to comprehensively test the effect of genetic variants in disease genes of interest. The staff scientist’s role will involve both wet lab and dry lab expertise.

Qualifications:

Expertise in computational analysis:

  • Fully comfortable using R or Python for data analysis
  • Fully comfortable performing appropriate statistical analyses
  • Expertise to the level of being able to train others

Expertise in molecular biology techniques:

  • Cloning and related molecular genetic approaches
  • Design and troubleshooting of experimental methods
  • Expertise to the level of being able to train others

Scientific independence:

  • Independently design experiments or projects
  • Build a command of the literature
  • Write manuscripts

Applicants should hold a Ph.D. or equivalent doctoral degree, as well as a strong record of publications that demonstrate their skill and expertise.

The ideal candidate will have molecular biology experience in yeast genetics, CRISPR, and/or high-throughput genetic screens, and computational experience analyzing next-generation sequencing data and/or experience with computing clusters such as Biowulf.

To Apply:

Applicants should send curriculum vitae and letter of interest to Meru Sadhu, meru@nih.gov, and arrange for three letters of recommendation to be sent as well.

Salary will be commensurate with education and experience. A full benefits package is available, including retirement, insurance, and leave benefits.

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.