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Protective Immunity to Intracellular Bacteria

Food & Drug Administration, Silver Spring, Maryland

Position Description:
A contract position is available immediately in the Elkins lab of the Laboratory of Mucosal Pathogens and Cellular Immunology at the Center for Biologics Evaluation and Research of the U.S. FDA (CBER / FDA). CBER is now located on the FDA's White Oak Campus in Silver Spring, MD; we continue to maintain strong ties to the NIH scientific community in Bethesda as well. CBER is a unique environment in which to conduct research related to the development of new biomedical products, especially new vaccines.
Our laboratory is interested in the nature of protective immunity to intracellular bacteria, including Mycobacterium tuberculosis and Francisella tularensis LVS. Current projects revolve around defining protective immune mechanisms in animal models and developing T cellmediated correlates of protection (for more information about the lab's work, please see recent publications via
http://www.ncbi.nlm.nih.gov/sites/myncbi/1LiW9NRGRNgQa/bibliography/47968487/public/?s
ort=date&direction=descending
).

Qualifications:
The ideal candidate will have a recent M.S. degree in microbiology and/or immunology; substantial bench experience related to the laboratory's work; intelligence, independence, and initiative; and excellent organizational, writing, and interpersonal skills. B.S. level candidates with applicable experience may also be considered. Experience with mouse handling, inoculation, and dissection; cellular and molecular immunology; flow cytometry; bacteriology; general molecular biology; microscopy; and BSL-3 work are of special interest. Candidates must be within 5 years of receiving their highest degree.

This position will have a yearly appointment with potential for renewal, contingent on excellent performance, via a fellowship from ORISE (see http://orise.orau.gov/fda/ and https://www.fda.gov/aboutfda/workingatfda/fellowshipinternshipgraduatefacultyprograms/ucm486289.htm). ORISE fellowships are available for U.S. citizens, non-citizens with permanent resident status, or non-citizens that are eligible for a J-1 visa (please note: only J-1 visas are acceptable). Applicants must also have lived in the U.S. for 3 of the last 5 years. Stipends correspond roughly to U.S. government GS scales, commensurate with education and experience, and include an allowance for mandatory health insurance.

To Apply:
Qualified candidates should send in electronic format: a short cover letter outlining research interests, research experience, and future goals; a detailed curriculum vitae that illustrates laboratory experience, responsibilities, and/or pertinent recent coursework; and names of at least 3 scientists or faculty as references (with contact information, including e-mail addresses and phone numbers); to Karen Elkins, karen.elkins@fda.hhs.gov. Applications will be reviewed until the position is filled.