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Drug Discovery Biologist at NIH/NCATS

Kelly Government Solutions, Rockville, Maryland

Position Description: 
Kelly Government Solutions is a strategic supplier and business partner to the federal government and its key suppliers.  Through our partnership with the National Institutes of Health, Kelly Government Solutions offers administrative, IT, engineering, scientific, and healthcare professionals the opportunity to work with one of the most prestigious research organizations in the world.  We are currently seeking a Drug Discovery Biologist to work with the National Institutes of Health in Rockville, MD. 

This is a long-term contract position which offers:

  • Competitive salary with comprehensive benefit package
  • Opportunity to work at NIH, world's foremost medical research center
  • Learn more about what Kelly can do for you at www.kellygovernmentsolutions.com

Duties:

  1. Independently propose new probe development projects in oncology and other biology areas
  2. Independently propose novel assay technologies and innovations that have the potential to improve the process of drug discovery
  3. Develop and optimize biochemical and cell-based assays for fully automated robotic screening in 384- and 1536-well format.
  4. Learn cell imaging instrumentation and apply to assays and screens; learn how to use cell imaging software analysis
  5. Analyze the experimental results and organize them into tables and figures with Prism Plot or other data analysis/visualization software like Spotfire.
  6. Evaluate new technologies and instruments resulting in proposals for new screening strategies and novel assay formats.
  7. Search existing literature; propose, design and test alternative assays for difficult screening targets.
  8. Confirm assay results and determine EC50/specificity for primary active samples; develop secondary assays for follow up; communicate results to facilitate small molecule probe development.
  9. Operate liquid dispensing systems (Aurora FRD, Kalypsys dispenser and pintool, CyBio CybiWell, PE Evolution P3) and multimodal detectors/plate readers (Tecan Safire, PE ViewLux, PE EnVision).
  10. Maintain and update laboratory notebooks and equipment.
  11. Write experiment reports and prepare manuscripts for publication in collaboration with other investigators.
  12. Independently co-write grant applications with NIH intramural as well as extramural academic investigators
  13. Prepare oral presentations and posters for internal and external groups/conferences.
  14. Propose, design and test assays to allow for a secondary profiling and utilization of probe candidates.
  15. Propose and investigate new target projects for initiation based on novelty and relevance to human health.
  16. Provide timely updates to assay providers; send summaries by email; conduct periodical teleconferences to discuss issues and coordinate actions.

Requirements:

  1. Ph.D. in Biochemistry, Cell Biology, Molecular Biology or a related discipline.
  2. Minimum of eight (8) years of experience related to drug discovery.
  3. Skill in maintaining accurate and detailed records of laboratory experiments.
  4. Strong communications skills, both oral and written.
  5. Excellent analytical, organizational and time management skills.
  6. Ability to multi-task, set priorities and pay close attention to detail.

To Apply:
Interested candidates should submit resumes to Susan LoCurto Schechter, Scientific Recruiter, at locursn@kellyscientific.com