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Staff Scientist: Immunity, Inflammation and Disease

National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina

Position Description:
The Immunity, Inflammation and Disease Laboratory of NIEHS is looking for a Staff Scientist for the Clinical Investigation in Host Defense Group under the group leader, Dr. Michael Fessler. The research focus of this group is in defining mechanisms of the innate immune response of leukocytes and the lung, in particular as they relate to host defense. Principal attention is directed at mechanisms by which cholesterol homeostasis regulates immunity, inflammation, and signaling responses of pathogen recognition receptors. Studies utilize in vivo mouse models, cell/molecular biology, genetic approaches, and biochemical techniques, and also translate findings using human/clinical specimens, when possible. Current research areas include sterols and oxysterols in immunity, epithelial regulation of lung inflammation, mitochondrial housekeeping and DNA damage in innate immunity, and interferon-induced immune-response genes. For more information about Dr. Michael Fessler and his research group, please visit:

A Staff Scientist is an NIH employee generally appointed to a time-limited, renewable position. Staff Scientists do not receive independent resources, although they often work independently and have sophisticated skills and knowledge essential to the work of the laboratory. Staff Scientists should be capable of independently designing experiments, but do not have responsibilities for initiating new research programs. The Staff Scientist in this position serves as a laboratory leader under the guidance of Dr. Michael Fessler, Principal Investigator, to conduct independent research, and to mentor postdoctoral fellows and other laboratory trainees.

The successful candidate will have the following knowledge, skills and abilities:

  • A doctoral degree in biological and/or biomedical sciences
  • Postdoctoral research fellowship experience, and an outstanding publication record
  • A strong background in in vivo (mouse model) immunological experimentation and expertise in multicolor flow cytometry are strongly preferred
  • Experience with metabolism as it impacts immunity (‘immunometabolism') is not required, but preferred
  • Successful candidate must also have outstanding interpersonal skills, teamwork, and excellent oral and written communication abilities

This is a federal, full-time equivalent position, and a comprehensive benefits package is available. Salary is commensurate with experience.

To Apply:
Interested persons should submit one combined PDF of their curriculum vitae and a two-page statement of research interests and goals, and also arrange for 3 letters of recommendation to be sent to Dr. Michael Fessler at Applications will continue to be accepted until vacancy is filled.

The NIH is dedicated to building a diverse community in its training and employment programs.
HHS and NIH are Equal Opportunity Employers. Applications from women, minorities, and persons with disabilities are strongly encouraged.