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Research Biologist

National Center for Advancing Translational Sciences, Rockville, Maryland

Position Description:

The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) is seeking a Biologist at our Rockville, Maryland location with expertise in assay development and translational research. NCATS establishes collaborations with disease experts around the world and utilizes high-throughput screening (HTS), bioinformatics, computational chemistry, and medicinal chemistry to discover and develop small molecule probes for therapeutic validation of biological targets and drug development.
The selected biologist will join a multidisciplinary team in an interactive laboratory environment. S/he will use cutting-edge cell biology and bioassay technologies for the development of disease relevant screening assays and will be involved in all aspects of the implementation of small molecule screening programs including assay design, assay development and optimization, high-throughput screening, data analysis, and follow-up studies in support of structure activity relationship (SAR) and mechanism of action studies for the development of novel pharmacological probes.
This individual will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. S/he will draft technical reports, manuscripts, and present work internally and to external collaborators as needed.


A PhD degree in cell biology, molecular biology, pharmacology, or related discipline and a minimum of 2 years of postgraduate experience are required. Experience with cell-based screening and reporter assays, HTS detection technologies, cell imaging, and/or cell engineering (e.g. CRISPR, molecular cloning) is highly desirable. Areas of special interest include cell stress, neuroscience, oncology, and target engagement assays. The candidate should be self-motivated, an independent thinker, a thorough and meticulous experimentalist, a team player, and able to multitask in an interactive setting. Effective communication and presentation skills are required. Applicants must be eligible to work in the US for any employer.

To Apply:

Please reach out directly to Mark Henderson ( if you are interested in applying for the position.