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Research Associate II

Frederick National Laboratory for Cancer Research, Frederick, Maryland

Position Description:

The Frederick National Laboratory is dedicated to improving human health through discovery and innovation in the biomedical sciences, focusing on cancer, AIDS, and emerging infectious diseases. 

The Clinical Services Program's primary mission is to perform sequential studies of immune function in patients with cancer, AIDS, chronic granulomatous disease or other diseases associated with immunologic dysfunction, as well as to monitor viral load in patients with HIV.

Responsibilities:

The Vaccine, Immunity and Cancer Program at the Frederick National Laboratory for Cancer Research is seeking a highly motivated individual with a strong background in immunology and molecular biology to investigate immune responses to HPV vaccines and HPV infection in clinical studies.

The Research Associate II will:

  • Optimize and validate procedures and methodologies for the assessment of immune responses to HPV vaccines in clinical studies
  • Plan experiments and conduct testing of a large number of samples using various immunological techniques, including ELISA, Luminex assays, and Virus Neutralization Assays from clinical trials
  • With limited supervision, design and implement protocols, as well as troubleshoot assays and experiments independently
  • Evaluate, analyze and compile data
  • Maintain databases
  • Be responsible for routine QC/QA procedures, ordering supplies, and maintaining equipment and inventories
  • Prepare reports, present data and participate in manuscript and proposal preparation     

Basic Qualifications:

  • Possession of a Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a related field (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to educational requirements, a minimum of five (5) years related biomedical experience
  • Detailed knowledge of vaccines, immunology, and virology
  • Strong expertise in tissue culture and immunological/virological techniques, including: aseptic techniques, cell line maintenance, production of plasmids and virus-like particles, western-blot, ELISA, Luminex assays, flow cytometry, virus neutralization assays and PCR
  • Experience handling human specimens and conducting immune monitoring testing in the context of human studies
  • Must be able to obtain and maintain a security clearance

Preferred Qualifications:

  • Master’s degree in immunology, vaccinology, virology or molecular biology
  • Experience in HPV research and high-throughput testing
  • Experience in assay development and validation under GCLP or GLP environment
  • Experience with large data sets, statistics, software tools (Word, Excel, PowerPoint)
  • Experience with robotics
  • Knowledge of regulatory requirements in vaccine development

To Apply:

If interested please contact Ligia Pinto at pintol@mail.nih.gov and apply at https://leidosbiomed.csod.com/ats/careersite/jobdetails.aspx?site=4&c=leidosbiomed&id=264