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Contract Scientist - Analytical Development

National Institute of Allergy and Infectious Diseases, Gaithersburg, Maryland

Position Description:

The position of Analytical Development Scientist, Bioassay /Bioseparation Group will support the Analytical Development group of the Vaccine Production Program (VPP) in the Vaccine Research Center.  The candidate will work within a team of scientists or lead a small team dedicated to the development of upstream, downstream and formulation development processes, that will significantly contribute to the clinical development of a variety of vaccine candidates and therapeutic biomolecule drug candidates. Clinical development products include monoclonal antibodies, recombinant proteins for vaccine candidates, including virus-like particles (VLP) and nanoparticles.  The position’s responsibilities will be to work independently within project teams to design, develop and optimize analytical assays and provide assay support for clinical trial vaccine candidates. The candidate may also be involved in method development and project support, as well as being involved in project presentations and cutting-edge scientific investigations.  

The primary responsibilities will be the design and execution of experiments required for the development of analytical assays required for development and clinical manufacturing.  Demonstrated analytical capabilities with techniques used in the analytical development in support of process and product development may include:
  • Binding assays
  • Gel Electrophoresis
  • Chromatography

Qualifications:

Bachelor’s degree, Master’s degree or PhD in biochemist or an immunologist or related discipline with relevant years of experiences and capabilities.
  • Ph.D. in a related scientific discipline, or:
  • Three (3) + years of specialized experience plus a Master’s degree, or:
  • Five (5) + years of specialized experience plus a Bachelor’s degree

A thorough understanding of protein analysis with experience in quantitative and qualitative protein analysis for assay development is required.  Knowledge of the requirements and experience developing, qualifying and/or validating assays for cGMP products and managing method transfers between laboratories is highly desirable.  The candidate will be involved in developing, characterizing and transferring assays to the VRC pilot plant’s QC group for product release.

The scientist will be expected to lead experimental design, carry out experiments, trouble shoot methods or help with trouble shooting material issues. They may also be called to initiate and lead experimental design. The candidate will be expected to write and review technical protocols and reports documenting analytical development studies pertaining to his/her work and the work of the group. 

This position will require close coordination with other team members as most projects require significant teamwork.  Therefore, the candidate must be a team player who can effectively work with other research, development and cGMP personnel.

To Apply:

Please Submit your CV to William Shadrick at the following email:

 

 

This post will be available until October 27, 2020 or until filled.

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