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Managing Director

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Position Description:

Due to the continued growth of the Center for Cytokine Storm Treatment & Laboratory (CSTL), we are searching for a Managing Director to lead and build the CORONA (COvid19 Registry of Off-label & New Agents) project, the world’s largest database dedicated to identifying and tracking all treatments reported to be administered to COVID-19 patients and building a new STORM (Systematic Tracker Of Repurposed/new Medicines) viewer. STORM will integrate and track all pre-clinical treatment data and clinical trial data and enable the search for patterns, identification of drugs that need to be evaluated in clinical trials, and facilitate recommendations to strengthen the global effort to combat COVID-19. Reporting directly to the Principal Investigator/Founding Director of the CSTL, the Managing Director will conceptualize and develop the work-plans, build the team, expand data analytic capabilities, collaborate with government, industry, philanthropic, and academic partners, and obtain further funding to achieve our overarching goal of accelerating the identification of effective COVID-19 treatments. Working independently, the Managing Director will be tasked with strategic direction of a major national initiative directed against COVID-19 and interface broadly with internal and external stakeholders from around the world to assure rapid progression of the science towards medical breakthroughs that help patients. He or she will recruit, train, supervise, and mentor CORONA personnel, graduate students, fellows, and scientific collaborators. transforming data into informative visuals, supporting database development, and collaborating with government, industry, philanthropic, and academic partners to achieve our overarching goal of accelerating the identification of effective COVID-19 treatments. He or she will work closely with the Project Manager to support successful project execution.
 
The CORONA (COvid19 Registry of Off-label & New Agents) project is the world’s largest database dedicated to identifying and tracking all treatments reported to be administered to COVID-19 patients. Housed within the Center for Cytokine Storm Treatment & Laboratory (CSTL) at the University of Pennsylvania, CORONA is providing real-time data and insights to guide clinical trial design and inform the global effort to identify treatments for COVID-19 in partnership with Google Health, FDA, Parker Institute for Cancer Immunotherapy, and others.
 
Due to the major unmet need, the CSTL, in partnership with the Division of Translational Medicine & Human Genetics and the Fajgenbaum lab, is now expanding CORONA to include a new STORM (Systematic Tracker Of Repurposed/new Medicines) tool and searching for a talented, experienced, and motivated Managing Director to oversee and direct the expansion and ongoing execution of CORONA. In addition to continuing to track all treatments administered to COVID-19 patients, STORM will also integrate and track all pre-clinical treatment data and clinical trial data and enable the search for patterns, identification of promising drugs that need to be evaluated in clinical trials, and facilitate the development of recommendations to strengthen the global effort to combat COVID-19. In one place, government agencies, academic researchers, philanthropic organizations, and biopharmaceutical companies will be able to access all data at no cost on all potential treatments for COVID-19. Working in partnership with the Director of the CSTL, the Managing Director of CORONA will be tasked with conceptualizing and developing the overarching strategy and approach to prioritize and execute data collection, building the team, expanding data analytic capabilities, collaborating with government, industry, philanthropic, and academic partners, and obtaining further funding to achieve our overarching goal of accelerating the identification of effective COVID-19 treatments. The strategy must be efficient given the extensive amount of data that exist and the urgent need for progress. It must also be flexible to meet the needs of new partners and program objectives in the short term and long term. Experience successfully leading a multi-stakeholder project with important implications as well as successfully obtaining funding is critical. This position offers the opportunity to contribute to the strategic direction of a major national initiative directed against COVID-19 and interface broadly with internal and external (federal government, pharmaceutical collaborators, non-profit partners, external academic collaborators, etc.) stakeholders from around the world to assure rapid progression of the science towards medical breakthroughs that help patients. He or she will report directly to the Principal Investigator/Founding Director of the CSTL and recruit, train, supervise, and mentor laboratory personnel, graduate students, fellows, and scientific collaborators.
 
Qualified candidates will have expertise in research planning, direct scientific leadership experience, advanced understanding of computational analyses, and familiarity with virology, immunology, and drug repurposing. This is a unique opportunity to join a highly motivated, patient-focused team that works closely with international collaborators and the federal government to make and publish novel discoveries that will have a significant impact on patients who have COVID-19 and other diseases with major unmet medical need.
 
***Contingent on Funding.
 
Duties:
· Conceptualize, design and execute research plans to build STORM to accelerate the identification of effective COVID-19 treatments.
· Recruit, train, supervise, and mentor a multi-disciplinary team
· Lead the expansion of the current database based on specific needs
· Engage with government, industry, philanthropic, and academic partners
· Help to obtain further funding for continued growth
 

Qualifications:

· MS + 5-7 years of a combination of relevant academic and work experience or equivalent combination of education and experience (e.g., PhD + 3-5 years) in biomedical sciences.
· Strong, proven supervisory and management experience required
· Experience with database development and computational analyses required
· Experience successfully securing grant funding desirable
· Experience interpreting computational analyses of immunology data desirable
· Familiarity with human immunology, virology, and drug repurposing a plus
· Experience with generating and interpreting high throughput drug screen data a plus
· Experience interpreting data from experiments on cell lines and animal models a plus
· Experience interpreting real-world data a plus
· Experience analyzing clinical trial data a plus
· Excellent organizational and time management skills
· Self-starter with a strong desire to contribute and work collaboratively to achieve goals
· Ability to work independently and apply critical thinking and sound judgment
· Ability to work with and take a leadership role in a multi-disciplinary team
· Ability to communicate effectively with team members
· Excellent oral/written communication skills with exceptional attention to detail.
· Strong computer/technology skills including database management, MS Excel, PowerPoint, and MS Project (or other similar Project Management).
 

To Apply:

To learn more about this opportunity and/or to apply visit the full listing here.  

If you have any additional questions after reviewing the full listing, please email CSTL@pennmedicine.upenn.edu.