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Process Development Engineer II/III

Adicet Bio, Redwood City, California

Position Description:

Adicet Bio, Inc is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. We are advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CAR) and T cell receptor-like antibodies (TCRL), to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. Our approach to activate, engineer and manufacture allogeneic gamma delta T cell product candidates derived from the peripheral blood cells of unrelated donors allows us to generate new product candidates in a rapid and cost-efficient manner. For more information, please visit our website at http://www.adicetbio.com.

PROCESS DEVELOPMENT ENGINEER II/III

Responsibilities:

  • Perform studies towards the development of CAR T products based on the T cell platform including media development, cytokine evaluation, MOI studies, transduction enhancer evaluation
  • Execute cell culture based experiments utilizing novel technologies to improve platform processes such as non-viral transduction strategies prior to transition to MS&T team
  • Create improvements to platform process for activation, transduction, and expansion unit operations
  • Perform multi-color flow cytometry acquisition and analysis
  • Tracking and ordering requisite consumables for PD and MS&T sub-teams
  • Accurately compile data in electronic notebook entries and aggregate data files

Qualifications:

  • BS/MS in Biochemical Engineering, Chemical Engineering, Science or Biotechnology.
  • BS with 5+ years or MS with 3+ years experience in industry setting
  • A strong background in cell therapy or CAR T products required
  • Experience in aseptic technique, cell culture, and retroviral or lentiviral transductions
  • Expertise with flow cytometry for T cells
  • Expertise with Microsoft Office suite, JMP, Prism, FlowJo, Benchling (or other electronic lab notebook software)
  • Experience with GMP processing and/or tech transfer related activities a plus
  • Assist in conducting analysis and reporting results, and interpretation of data.
  • Possesses good verbal and written communication skills
  • Ability to operate in a fast paced, industrial environment
  • Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

Benefits:

  • Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

To Apply:

Please visit this webpage and search for "Process Development Engineer II/III" to apply for the position: https://www.adicetbio.com/careers/openings/

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.