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Research Associate/ Senior Research Associate, Research: T Cell Immunology, CAR T Cell

Adicet Bio, Redwood City, California

Position Description:

Adicet Bio, Inc is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for cancer. We are advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CAR) and T cell receptor-like antibodies (TCRL), to enhance selective tumor targeting, facilitate innate and adaptive anti-tumor immune response, and improve persistence for durable activity in patients. Our approach to activate, engineer and manufacture allogeneic gamma delta T cell product candidates derived from the peripheral blood cells of unrelated donors allows us to generate new product candidates in a rapid and cost-efficient manner. For more information, please visit our website at http://www.adicetbio.com.

RESEARCH ASSOCIATE / SENIOR RESEARCH ASSOCIATE,
RESEARCH: T CELL IMMUNOLOGY, CAR T CELL

We are seeking a highly motivated candidate with a research background in immunology to join the Adicet Research Team. The ideal candidate will have in-depth knowledge of T cell immunology and CAR-T cell development. The candidate will work as a part of a multidisciplinary team, utilizing the latest technologies for cell engineering and contributing to the generation of novel cell-based therapeutics for the treatment of cancer.

Responsibilities:

  • Perform gene edits on cell lines and primary cells
  • Design, perform, and analyze in vitro experiments to characterize CAR-T cell function
  • Cell culture (primary cells, cancer cell lines, CAR-T cells) for cell-based assay development (proliferation, cytokine release, cytotoxicity)
  • Apply nucleic acid, protein, and reporter-based technologies (e.g., Nanostring, Luminex, Incucyte) for assay analysis
  • Perform multi-color flow cytometry (cell surface/intracellular staining, cell sorting)
  • Maintain detailed records of experimental protocols, results, and inventory in an electronic lab notebook
  • Analysis and interpretation of experimental data
  • Present at group meetings
  • Utilize software tools to support data analysis tasks (e.g., Prism, FlowJo, Word, Excel and PowerPoint)

Qualifications:

  • BS or MS in biological sciences or a related field
  • 2+ years of relevant industry experience
  • Experience in primary cell culture and aseptic tissue culture techniques is required.
  • Experience with cell-based assays (e.g., CAR-T and cancer cell co-culture cytotoxicity, cytokine, proliferation, and serial stimulation assays)
  • Experience with multicolor flow cytometry and data analysis on FlowJo is a plus.
  • Ability to work collaboratively, multitask and meet deadlines in a fast-paced environment
  • Openness to flexible working hours is preferred
  • Organized and disciplined record keeping is essential
  • Team player with excellent verbal and written communication skills
  • Adicet Bio requires all workers to be fully vaccinated against COVID-19, including the booster dose.

Benefits:

  • Adicet Bio offers both comprehensive benefits and Paid Time (PTO) plans for employees, which begin on the first day of employment, as well as the opportunity to work in a growing, dynamic environment.

To Apply:

Please visit this webpage and search for "Research Associate/ Senior Research Associate, Research: T Cell Immunology, CAR T CELL" to apply for the position: https://www.adicetbio.com/careers/openings/

Adicet Bio is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.