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Staff Scientist, Thymus Biology Section

National Cancer Institute, Bethesda, Maryland

Position Description:

  • Conduct laboratory-based research on the molecular mechanisms regulating gene expression.
  • Perform a wide range of sophisticated genetic, biological, and biochemical assays, including but not limited to the production and analysis of mutations within genes, DNA transfection of cells, monolayer and anchorage-independent growth assays, immunoprecipitation assays, agarose gel electrophoresis, and in vivo and in vitro kinase assays.
  • Perform a wide range of in vivo studies on the roles of transcription factors in tissue specific gene expression.
  • Work with the scientific staff to define key questions emerging from research projects in which experimental in vitro and in vivo analysis will contribute to elucidation of fundamental mechanisms of gene regulation.
  • Collaborate with scientists and statisticians in NCI, NIH, and extramural research institutions as appropriate, to advance the research projects and elucidation of project data.
  • Perform studies that result in peer reviewed articles describing advances in molecular immunology.
  • Collaborate with NIH/NCI expert staff to clarify needs and project objectives.
  • Initiate, design, and develop new projects or assays that can enable the Center for Cancer Research/Experimental Immunology Branch to fulfill its responsibilities for advancing our understanding of mechanisms of immune regulation.
  • Serve as an authority on gene expression and chromatin biology that is being studied and the assays that are being performed.
  • Interpret results of initial analysis to reveal conclusions and shortcomings; identify pitfalls in the original choice of methods or experimental direction; redirect the study to achieve improved results.
  • Identify the need for further investigations and/or propose change in direction of work considering accomplishments, findings, and current and future mission objectives.
  • Attend seminars within the National Institute of Health/Center for Cancer Research/ Experimental Immunology Branch; pursue additional training, where necessary; participate in discussions at meetings.
  • Make oral presentations at Branch Seminars, Joint Group meetings, and as invited.
  • Prepare data sets, Tables and Figures for collaborative papers prepared for publication in peer-reviewed journals; assemble and write papers for first-author publication in peer-reviewed papers. EIB,NCI,NIH


  • Ph.D. in biology or related field
  • Minimum four (4) years of experience in thymus biology
  • Minimum of one first author and one middle author paper in peer reviewed journals
  • Strong communications skills, both oral and written.
  • Excellent analytical, organizational and time management skills.

To Apply:

Please submit CV's to Caroline McCabe

The NIH is dedicated to building a diverse community in its training and employment programs and encourages the applications and nomination of qualified women, minorities, and individuals with disabilities.