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Malaria Vaccine

Walter Reed Army Institute of Research, Silver Spring, Maryland

Position Description:
A post-doctoral fellowship under the NRC Research Associateship Program is available starting summer of 2018 at the Malaria Vaccine Branch, Walter Reed Army Institute of Research. The candidate will develop monoclonal antibody based prophylactic agents against malaria targeting both liver and blood stages of the parasite. Ph.D in molecular biology, biochemistry, immunology or a related field is required. Work will involve a range of preclinical product development activities including: antibody scaffold design, protein expression, antibody engineering, mammalian cell expression, antibody humanization, affinity maturation. Bench-work will involve molecular biology techniques like gene cloning, construct design, site-directed mutagenesis, mammalian and/or eukaryotic expression protein purification, transfection, biochemical and biophysical characteristics of antibodies, stability, affinity measurements, binding kinetics, epitope determination, protein sequence and structure analysis using DNASTAR, PYMOL or similar software.

The candidate needs to be able to analyze and interpret experimental results, plan experiments and use statistical tools. Hands on experience in multiple expression systems and phage display will be a plus. Fellow will be required to follow laboratory safety regulations and attend government mandated trainings to work at the institute.

To Apply:
Please contact Sheetij Dutta, Ph.D. via email: