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CRISPR/Cas9 and ChIP Seq

University of Maryland School of Medicine, Baltimore, Maryland

Position description:

Research in my laboratory is focused on understanding the mechanisms of cardiovascular development and promoting adult heart regeneration. One of the major focuses of our research is to identify the novel signaling pathways that regulates myocardial development by using in vitro and in vivo approaches. Another interest is to identify genes/factors that can promote heart regeneration.

Mouse and cell model systems, including conditional gene knockouts, will be used in these research projects, and many state of the art techniques are employed, such as real time PCR, CRISPR/Cas9 Genome Editing, AAV vectors, RNA-Seq and ChIP Seq, confocal microscopy, real time imaging and advanced microscopy, multicolor flow and sorting, surgical models, ultrasonic and telemetric measurements of cardiovascular function in mice. The University of Maryland School of Medicine has a group of outstanding scientists in cardiovascular research, especially in cardiovascular cell signaling, diabetes, endothelial biology, and pathogenesis of atherosclerosis. Successful applicants will have the opportunity to work with them and get help in developing an independent career in this research field.


Applicants must have a PhD, MD/PhD or equivalent degree and proven skills and experience in molecular biology. We are seeking talented and self-motivated postdoctoral candidates with a good work ethic, and a strong interest in cardiovascular development and regeneration.  Candidates with background and experience in CRISPR/Cas9, IPSC cell culture, sequencing, and mouse in vivo studies are preferred.  Good writing and oral communication skills in English are required as well as the ability to work both independently and collaboratively.

To Apply:

Interested candidates should send cover letter, CV and contact information for three references. Please send your application as a single PDF file to Dr. Deqiang Li:  Review of applications will continue until the position is filled.