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Molecular Biophysics

University of Mississippi, Oxford, Mississippi

Position Description:

The Molecular Biophysics and Engineering Lab in the Department of Biomedical Engineering at the University of Mississippi is seeking a full-time Postdoctoral Research Associate to lead the development of new experimental assays for understanding the mechanics of cytoskeletal crosstalk using optical tweezers and other biophysical approaches. The goal of the lab’s work is to understand how cytoskeletal protein ensembles work together and communicate at the
molecular level to facilitate large scale cellular tasks, such as division and muscle contraction, as well as identify mechanisms of disease.


  • The ideal candidate will have a Ph.D. (or soon to be awarded Ph.D.) in biophysics, engineering, biochemistry, or closely related field and experience in experimental biophysics.
  • The candidate should have familiarity with in vitro reconstitution, microscopy, and the cytoskeleton.
  • Strong interpersonal skills necessary for a highly collaborative and inclusive environment, excellent communication skills (oral and written), and a proven track record of research evidenced through
    peer-reviewed publications and conference presentations are required.
  • Interest in leading the establishment of new skill sets within the lab, such as cell culture, protein expression and purification, preparation of cytoskeletal proteins from tissue, and/or computational modeling of protein ensembles is desired but not required.


  • Lead the development of new in vitro cytoskeletal assays using biophysical experimental techniques, such as optical tweezers, fluorescence microscopy, and QCM-D
  • Interrogate the physical properties cytoskeletal building blocks using spectroscopic and computational approaches
  • Innovate assay designs and approaches as needed and informed by experimental results
  • Generate, compile, and interpret experimental data from in vitro studies
  • Assist with daily lab operations and with mentoring junior lab members
  • Develop and contribute to grant reports, new grants, manuscripts, and conference presentations

To Apply:

Interested applicants should apply at: by submitting a combined PDF of the following: cover letter, curriculum vitae, two sample publications, and contact information for three
references. The cover letter should clearly state the candidate’s research experience, interest in the lab, and future career goals. Any inquiries related to the position can be sent to Dr. Nikki
Reinemann (