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Postdoctoral Fellow

NCATS, Bethesda, MD and surrounding area

Position Description:

We are seeking a self-motivated postdoctoral fellow to work on the Tox21 research projects in development of physiologically relevant assays for assessment of environmental chemicals. The NCATS has a unique and exciting environment employing state-of-art technologies on assay development, chemical screening, and profiling for toxicology research.

The fellow will develop in vitro cell-based assays using physiologically relevant cell models (primary cells, stem cell/iPS-derived cells, and 3-D cell/organoid models) with biotransformation-capability for screening chemicals. The fellow will apply new technologies including 3-D cell/organoid models and high content phenotypic profiling using cell-based imaging assays for evaluating chemical toxicity. The fellow will perform follow-up studies (e.g., mechanisms of compound action) after the primary screening. The fellow will also interact regularly with informatics scientists to aid data analysis and interpretation.


Minimum requirements include a Ph.D. degree in life science fields including toxicology, pharmacology, biology, cell biology, and biochemistry, with solid understanding of toxicology, cell biology, or general aspects of signal transduction. Experience in assay development including biotransformation-capable assays, imaging technology, or compound screening is a plus. Basic data analysis skills and familiarity with Excel spreadsheets are desired. Effective oral and written communication skills combined with high level of motivation and ability to thrive in an interactive, fast-paced environment are also preferred.

To Apply:

Applicants should send a letter stating their research interests and goals, a CV including bibliography, and arrange for three letters of reference to be sent by e-mail to the respective scientific contacts.

Menghang Xia, Ph.D.,

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.