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Chimeric Antigen Receptor T-Cell Therapies

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:

One fully funded postdoctoral position is available for a highly motivated individual to study cancer immunotherapy at the National Institutes of Health, National Cancer Institute. The position is in the lab of James N. Kochenderfer. Projects will focus on translational research aimed at developing new T-cell therapies for cancer. The overall goal of the group is improving treatment for hematologic malignancies by developing new therapies that utilize T cells expressing chimeric antigen receptors (CARs) or new T-cell receptors (TCRs). A wide variety of activities are carried out by the group including development of new CARs and TCRs, identifying new CAR targets, targeting cancer-specific mutations, and optimizing gene therapy technologies. Techniques used include cellular immunology including flow cytometry, various types of next-generation sequencing, murine models of hematological malignancies, design and construction of new CARs, and clinical trials of T-cell therapies. Ample funding and core laboratory support are available.


Applicants must have experience with flow cytometry and working with mice. Experience in T-cell immunology or bioinformatics is desirable but not required. Interested candidates must have a doctoral degree with four years or less of postdoctoral experience. A record of publication in immunology, gene therapy, or molecular biology along with good writing and presentation skills are required for selection. This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.

To Apply:

Please email your CV and names of 3 references to Dr. James Kochenderfer

More information is available at this link:

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.