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Cancer Biology and Genetics

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:

A postdoctoral position is available in the Cancer Molecular Pathology section headed by Frederic G. Barr, MD PhD in the Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD. This research laboratory uses a multidisciplinary approach involving genomics and bioinformatics along with cell culture and animal models to study genetic and epigenetic alterations in cancer. By initially focusing on specific cancer types, such as the rhabdomyosarcoma family of myogenic soft tissue cancers, this research laboratory is investigating the molecular basis, biological consequences and clinical significance of chromosomal translocations, amplification events, and methylation changes in these cancers. The methodologies, reagents and concepts from these studies are then being applied to address these issues in other relevant cancer categories. This is an exciting opportunity to join a growing and evolving cancer research effort across the basic, translational, and clinical research spectrum. Current projects in the laboratory are in the areas of:

  • Action of fusion oncoproteins (J. Pathol. - PMID: 28138962)
  • Mechanisms of tumor recurrence (Cancer Res. - PMID: 33589519)
  • Amplified genes as therapeutic targets (J. Clin. Invest. - PMID: 34166228)
  • DNA methylation-based classification (Int. J. Cancer - PMID: 30565669).

Qualifications:

Interested candidates must have a doctoral degree with less than five years of relevant postdoctoral experience, and have a background in molecular biology, cell biology, biochemistry, genetics, or a related discipline.

To Apply:

Candidates should send CV including list of publications, cover letter, and names/contact information of three references to Frederic G. Barr, MD PhD at barrfg@mail.nih.gov.

This position is subject to a background investigation. DHHS, NIH and NCI are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.