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Functional Cancer Genomics

National Human Genome Research Institute, Bethesda, MD and surrounding area

Position Description:

The Bell laboratory is seeking a highly-motivated Postdoctoral candidate committed to research into the molecular underpinnings of human cancer. The overarching goal of the laboratory is to identify pathogenic driver genes that underlie the development of the most clinically aggressive forms of human endometrial cancer. Our research entails the functional annotation of somatic mutations in candidate driver genes previously identified by next generation sequencing of endometrial tumor tissues. The successful applicant will apply detailed molecular, biochemical, and cellular approaches to functionally discriminate driver mutations from passenger mutations in selected genes-of-interest. Access to extensive core facilities including cores in bioinformatics, microarrays, copy number analysis, flow cytometry, cytogenetics, and a transgenic mouse core, offers the trainee wide latitude in the design and pursuit of their research questions. Extensive career development opportunities are available through the NHGRI Intramural Training Office and the NIH Office of Intramural Training and Education. The Intramural Research Program is on the Bethesda campus and offers a wide array of training opportunities for scientists early in their careers.


Successful candidates should have or be very close to obtaining a PhD, and have less than two years of Postdoctoral experience. Applicants should have a strong background in cancer research, as well as proven expertise in molecular/cellular biology and biochemistry. A demonstrated record of scientific accomplishment evidenced by at least one first-author paper, a strong work ethic, and strong intellectual commitments to cancer research and to the individual research project, are essential. The successful candidate should possess excellent interpersonal and organizational skills, and stellar communication skills with fluency in both spoken and written English.

To Apply:

Suitably qualified candidates should submit their curriculum vitae, cover letter, and names and contact information for three referees to Dr. Daphne W. Bell at

Salary will be commensurate with research experience.

The NIH is dedicated to building a community in its training employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.