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Role of BRCA2-Loss Induced Genomic Instability on Cell Viability and Drug Resistance

National Cancer Institute, Frederick, MD

Position Description:
The Genetics of Cancer Susceptibility Section in the Mouse Cancer Genetics Program at NCI is seeking a highly motivated postdoctoral researcher to investigate the role of BRCA2 induced genomic instability on cell growth, tumorigenesis and drug resistance using genomic profiling and computational approaches in mouse embryonic stem cells and knock-in mouse models.

Applicants must have a Ph.D. and/or M.D. or equivalent degree. A strong background in molecular biology and cancer genetics is required. Knowledge of DNA repair and bioinformatics is desirable.  Candidates must have excellent communication skills. The position is available immediately.

To Apply:
Applications, sent by e-mail to, Phone (301) 846-5140, should consist of a cover letter describing research experience and interests, curriculum vitae, bibliography, and contact information for three references (including the current supervisor).

For additional information please visit PubMed Summary and Dr. Sharan's webpage

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.