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Cancer Immunology/Immunotherapy

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:
The Laboratory of Tumor Immunology and Biology (LTIB) functions as a multidisciplinary and interdisciplinary translational research programmatic effort with the goal of developing novel immunotherapies for cancer. The LTIB strategic plan focuses on the development of novel immunotherapeutics for human cancer, not only as monotherapies, but more importantly, in combination with other immune-mediating modalities, and other conventional or experimental therapies, as part of an lmmuno-oncology programmatic effort. Within this effort are several research groups, a clinical trials group, and multiple collaborations with Intramural and extramural scientific and clinical investigators and with investigators in the private sector.

The program takes advantage of the uniqueness of the NCI, Center for Cancer Research Intramural program in that it spans high-risk basic discovery research in immunology genomics and tumor biology, through preclinical translational research, to paradigm-shifting clinical trials. Focus is placed on the design and development of novel "off-the-shelf" recombinant (rec.) immunotherapeutics that can be used in clinical studies at numerous institutions. A major strength of the program Is the rapid translation of preclinical studies to hypothesis-generating clinical trials.

The Center for Cancer Research (CCR) is the intramural research component of the NCI. CCR's enabling infrastructure facilitates clinical studies at the NIH Clinical Center, provides extensive opportunities for collaboration, and allows scientists and clinicians to undertake high-risk, high-impact laboratory- and clinic-based investigations. Investigators are supported by a wide array of intellectual, technological, and research resources, including animal facilities and dedicated, high-quality technology cores in areas such as imaging/microscopy, chemistry/purification, mass spectrometry, flow cytometry, genomics/DNA sequencing, transgenics and knockout mice, arrays/molecular profiling, and human genetics/bioinformatics. For an overview of CCR, please visit

We are looking for postdoctoral fellows interested in learning immunology and immunotherapy, as well as those postdoctoral fellows with a background and/or interest in experimental pathology. Candidates are required to have a PhD or MD degree, or equivalent, in immunology, molecular/cell biology or experimental pathology. The position is available immediately. The appointment duration is up to 5 years. Stipends are commensurate with education and experience. Multiple positions available.

To Apply:
Applicants should submit a cover letter describing their research experience and interests, CV including bibliography, and contact information for three references to: Dr. Jeffrey Schlom, Ph.D., via e-mail: No calls, please. lf we are interested, you will be contacted by Dr. Schlom.

Additional information can be found on the LTIB website:  and on Dr. Schlom's profile page:

DHHS, NIH, and NCI are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.