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Epigenetics/Systems Biology Postdoctoral Researcher

National Heart, Lung and Blood Institute , Bethesda, MD and surrounding area

Position Description:
The National Heart, Lung, and Blood Institute (NHLBI), a major component of the National Institutes of Health (NIH), Department of Health and Human Services has an opening for an Epigenetics & Systems Biology postdoctoral researcher to study immune memory, cellular differentiation, and pathological conditions using genomics, epigenomics and systems biology approaches. Our laboratory has developed the ChIP-Seq, MNase-Seq, single-cell DNase-seq, and 3e Hi-C techniques to analyze genome-wide distribution of chromatin modifications and DNA-binding factors [Cell, vol 129, p823-837 (2007); Cell vol 132, p887-898 (2008); Cell, vol 138, p1019-1031 (2009); Cell, vol 151, p68-79 (2012); Nature vol 528, 142-6 (2015); Mol Cell vol 67, p1049-1058 (2017); Nat. Immunol. Vol 18, p1035-1045 (2017)].

Using these powerful techniques, we are studying the contribution of two-dimensional and three-dimensional nuclear structure to normal development and diseases. Future studies will investigate the function and regulation of three-dimensional nuclear structure during differentiation of hematopoietic stem cells to T cells. The incumbent will focus on bench work or computation work or both depending on previous training and expertise. Opportunities for extensive collaborations with the research communities are available.

The ideal candidate must have a Ph.D. in Molecular Biology or Biochemistry or computational biology with a strong record of publication. The candidate must have received a Ph.D. within the past three years.

The candidate will be supported with an excellent intramural NIH fellowship in a stimulating and interactive research environment at NIH. Salary is commensurate with research experience and accomplishments.

To Apply:
Send curriculum vitae and names and addresses of three references to:

Keji Zhao, Ph.D.
Director and Senior Investigator
Systems Biology Center
Division of Intramural Research
National Hear Lung and Blood Institute, NIH
Bldg.10, Rm.7B05
9000 Rockville Pike, Bethesda
MD 20892-1674

DHHS/NIH is an Equal Opportunity Employer. The NIH is dedicated to building a diverse community in its training and employment programs.