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Postdoctoral Position in Structural Biology

National Institute of Environmental Health Sciences, Bethesda, MD and surrounding area

Position Description:

The research group of Dr. Robin Stanley at the National Institute of Environmental Health Sciences is seeking candidates for postdoctoral fellows. The broad interests of the lab are in the structure and function of RNA processing machines. We combine structural techniques including macromolecular crystallography, cryo-EM, and small angle x-ray scattering with biophysical, biochemical, and cell based methods. Additional information can be found at https://www.niehs.nih.gov/research/atniehs/labs/stl/pi/nucleolar/index.cfm.

For examples of our recent work please see:

Lo, Y.H. et al. (2019) Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7. Nat Commun, 10, 513.

Pillon, M.C. et al. (2018) Characterization of the molecular crosstalk within the essential Grc3/Las1 pre-rRNA processing complex. RNA, 24, 721-738.

Pillon, M.C. et al.(2017) Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage. Proc Natl Acad Sci U S A, 114, E5530-E5538.

Lo, Y.H. et al. (2017) Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2. Structure, 25, 762-772 e764.

The NIEHS is located in the Research Triangle Park (RTP) area of North Carolina, one of the largest high-tech research parks in the world. In addition to being a world-renowned academic intensive research center, the RTP area is well known for its high quality of life. Fellows will also have access to the NIEHS’s state-of-the-art research core facilities including a flow cytometry center,  fluorescence microscopy and imaging center,  a mass spectrometry center, epigenomics core laboratory, structural biology core, and a newly established cryo-EM facility.

Qualifications:

Candidates must have a Ph.D. and/or M.D. degree (or anticipate receiving their degree in the near future), be author of at least one first author publication, and have experience in structural biology, molecular biology, biochemistry, or biophysics. Candidates should have less than 5 years of post-doctoral experience.

To Apply:

Please send a cover letter detailing your current and future research interests, your CV, and contact information for 3 references by email to Dr. Robin Stanley (Robin.stanley@nih.gov).

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