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Proteomics of Retinal Pigment Epithelium

National Eye Institute, Bethesda, MD and surrounding area

Position Description:

The group of Dr. T. Michael Redmond in Molecular Mechanisms Section, Laboratory of Retinal Cell & Molecular Biology (LRCMB), National Eye Institute (NEI), NIH, is seeking to recruit an outstanding post-doctoral fellow to study proteomics of the retinal pigment epithelium (RPE). The broad interests of our group are in the biochemistry and molecular biology of the retina and RPE; RPE visual cycle retinoid metabolism; other characteristic processes of RPE; and the role of noncoding RNAs in RPE gene regulation. We investigate the role of these processes in vision, in blindness, and towards strategies to reverse these conditions. Many blinding diseases (inherited and age-related) involve derangement of these key RPE processes. As RPE is a highly metabolically and physiologically specialized tissue we are investigating in depth the sub-proteomes of its organelles to better understand the role of RPE in health and disease.

Our group interacts with several other NEI and NIH labs in various aspects of biology and biomedicine (biochemistry, biophysics, “omics”, molecular genetics, molecular biology, etc.), and the successful applicant will have opportunities to collaborate with these labs and groups, as well as extramurally.

Qualifications:

  • Candidates must hold an M.D./Ph.D. or Ph.D. in a cognate field, within five years of degree being awarded;
  • Must have first authorship on at least one peer-reviewed publication;
  • Have strong training in biochemistry/proteomics/structural biology with experience in protein/cellular fractionation/purification and protein characterization;
  • Prior experience in proteomics, membrane protein biochemistry, mass spectrometry (LC-MS/MS or MALDI-TOF MS) will be an added advantage;
  • Have excellent writing and communications skills;
  • Candidates must be highly motivated and keen to develop technical expertise and career-enhancing skills;
  • The ability to work as part of a cohesive group is important as we are a highly collaborative lab.

To Apply: 

Interested candidates can send an email of interest to redmondd@nei.nih.gov with a CV, names and contact info for 3 references, a one-page statement of interest, and a summary of previous research experience and future career interests.

The NIH is an equal opportunity employer. The NIH is dedicated to building a diverse community in its training and employment programs.