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Discovery Research on Viral Malignancies

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:

We are searching for a highly motivated and creative postdoctoral fellow interested in translational research related to "viral cancer development, clonal evolution and treatment". The focus of this research is on the molecular mechanisms that underlie cell-to-cell communication within the tumor microenvironment and how such interplay contributes to cell evolution into a cancer cell, cancer progression and response to treatment. This research will be carried out in an exciting environment of creative, dedicated and successful scientists.

The position is located in the Molecular and Cell Biology Section (Dr. G. Tosato) of the Laboratory of Cellular Oncology, CCR/NCI/NIH.

Qualifications:

The candidate should have evidence of excellent training and productivity, should demonstrate genuine interest in contributing to advances in cancer research and should be able to communicate effectively in writing and verbally. A virology, molecular biology and cell biology background is desirable. The candidate should possess experience in all or some of the following: molecular biology and biochemistry, including construction of lentiviral expression systems, CRISPR-Cas9 gene editing systems, transient and stable gene expression/silencing, PAGE and immunoblotting, quantitative PCR, luciferase-based promoter analysis, chIP assays and analysis of signaling pathways; cell biology, including cell separation, cell-based functional studies, FACS analysis, immunostaining, confocal microscopy; mouse models of cancer, including maintenance of mouse colonies, derivation of mouse strains of interest, handling of mice for cancer-related in vivo experiments, mouse injections, blood drawing, tissue procurement, genotyping and statistical analyses for design and evaluation of pre-clinical cancer models.

To Apply:

Please submit the following: CV and publication list; a list of References; a statement of interest and employment goals. Submit information to: tosatog@mail.nih.gov (preferably) or mail to Dr. G. Tosato, LCO/CCR/NCI, Building 37/room 4124, Bethesda, MD 20892.

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs. The NIH is an equal opportunity employer.