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Computational Biologist- Lung cancer, DNA Repair and Replication

National Cancer Institute, Developmental Therapeutics Branch, Bethesda, MD and surrounding area

Position Description:

A postdoctoral computational biology scientist position is immediately available. The individual will be part of a team focused on translational research of lung cancer. Our goal is to integrate the molecular profiling and phenotype data to define patient subgroups. The position involves bioinformatics and computational biology investigation of clinical and preclinical data and offers an opportunity to work on projects which will have an impact on patient care.

Key responsibilities include:
  • Advanced analysis of DNA-seq, bulk and single cell RNA-seq, ChIP-seq and other sequencing data in combination with publicly available genomics data by applying unsupervised and supervised machine learning algorithms to extract novel and biologically meaningful information.
  • Method development for translational research, e.g. predictive modeling for patient stratification.
  • Integrates genomics, genetics, epigenetics and literature data to strengthen understanding of diseases and treatment perturbations.
  • Utilizes multiple approaches for analyses of genes, pathways and networks.
  • Writes study reports and presents data effectively in all settings and with participants of all levels of the organization.


  • A Master’s degree, PhD or equivalent in bioinformatics, computational biology, or a related field. • Strong programming skills in R, Python, and/or other languages commonly used for bioinformatics analysis. Must be expert in applying major bioinformatics tools.
  • Hands on experience in using public human genetics and epigenetics databases.
  • A background in basic cellular and molecular biology is preferred.
  • Strong communication and team working abilities to contribute in a team that operates as a unit on large projects.
  • Be expert in sequencing data analysis such as RNAseq, DNAseq, scRNA-seq, etc.
  • Background in cancer is a plus.

To Apply:

Please send a cover letter with past research accomplishments and future research interests, a CV with a publication list, and the contact information of three references to


This post will be available September 18, 2020 until or until filled.

This position is subject to a background investigation.

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