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Computational Scleroderma Genetics

National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD and surrounding area

Position Description:

A postdoctoral fellowship position is available immediately in the Scleroderma Genomics and Health Disparities Unit at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), NIH. The position is based in Bethesda, Maryland.

We are seeking a highly motivated postdoctoral candidate committed to use computational methods in the study of mechanism involved in the field of autoimmunity. The goal of the Gourh Lab is to understand the genetics of a rare autoimmune disease, systemic sclerosis (scleroderma). We have put together the largest collection of African American scleroderma samples in the world and have undertaken a comprehensive genetic study design to understand this complex condition. The position would entail analyzing data from SNP genotyping, high-throughput DNA sequencing methods for a variety of assays, including exon sequencing, RNA-seq, ATAC-seq, and ChIP-seq.

Experience with genome-wide association studies (GWAS) and large data SNP imputation will be preferred.

Qualifications:

The ideal candidate will have a PhD in genetics, bioinformatics, or biostatistics, and experience with basic molecular biology techniques. Individuals with an MD and research experience will be considered. Candidates must be within five years of graduation. The individual should be strongly motivated and be willing to work both independently and collaboratively as a member of an active research group.
  • PhD degree in computational biology, bioinformatics, biostatistics, genetics or other quantitative fields
  • An ability to program in Python/Perl and R/Matlab in Unix environment are preferred
  • Experience with PLINK and genetic Imputation pipelines
  • Self-motivated with excellent communication skills and strong capability to interact with bench scientists
  • Knowledge of molecular biology will be a plus

To Apply:

Interested candidates should submit a cover letter, current curriculum vitae, publication record, and names and contact information for three referees to Dr Pravitt Gourh at pravitt.gourh@nih.gov.

 

This post will be available until September 26, 2020 or until filled.

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