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Stem Cell Toxicology and Molecular Biology

National Institute of Environmental Health Sciences, Research Triangle Park, NC

Position Description:

A Postdoctoral position is available immediately within the Laboratory Branch of the National Toxicology Program (NTP) at National Institute of Environmental Health Sciences (NIEHS) in Research Triangle Park, NC. The position will work collaboratively with the Molecular Genomics Core in the Division of Intramural Research (NIEHS) and Biomolecular Screening Branch at NTP/NIEHS (https://www.niehs.nih.gov/).

We are seeking an independent and self-motivated individual to study released, cell-free biomolecules in embryogenesis and lineage specification in cell culture models. The projects involve using pluripotent and multipotent stem cells, established 2D and 3D cell models, and studying the biological effects of cell-free DNA (cfDNA) and other released biomolecules (e.g. RNA, ncRNAs in extracellular vesicles). The research will focus on the normal, temporal changes in circulating biomolecules during embryogenesis and lineage specification and the chemically-induced effects on these biomolecules during those processes. These studies will investigate the roles of released RNA, DNA and ncRNAs in the screening and identification of possible developmental toxicants.

Qualifications:

  • Recent PhD degree in toxicology, developmental biology, or related field.
  • Background in stem cell biology/toxicology or cell biology is desired.
  • Experience with in stem cell techniques (e.g. maintenance, differentiation protocols, etc.) and molecular biology techniques (e.g. nucleic acid extraction, PCR, NGS, imaging, cell-based assay development, etc.) is preferred. 
  • Experience with 2D and 3D cell culture models, biochemistry, and high-throughput screening is a plus.
  • Excellent oral and written communication skills, as demonstrated by a strong publication record and presentations at scientific meetings.    
  • Excellent organizational and interpersonal skills and an ability to work on a multi-disciplinary team.

To Apply:

Interested candidates should submit the following application materials as a single PDF file to Dr. Erik Tokar (erik.tokar@nih.gov):
  • Cover letter which describes why you would be a suitable candidate for the position
  • Up-to-date CV which includes list of publications
  • hTree (3) letters of reference
  • Copies of doctoral degree certificate

 

This post will be available until September 27, 2020 or until filled.

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