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Environmental Regulation of the Estrogen Response in Single Cells

National Institute of Environmental Health Sciences, Research Triangle Park, NC

Position Description:

A postdoc position is available in the laboratory of Dr. Rodriguez in the Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH in Research Triangle Park, NC.  We are interested in understanding how single cells make decisions and how environmental stimuli influence these processes.  Our long-term goal is to determine how heterogeneity in the estrogen response contributes to tissue function and disease.  The lab uses a variety of imaging and sequencing approaches including live cell single-molecule microscopy to characterize enhancer, gene and protein expression dynamics.  Projects in the lab include determining how the microenvironment and chemical exposure affect estrogenic transcriptional activity in breast cancer cell lines, organoids and mice.


PhD in molecular/cell biology, genomics, biochemistry or relevant field. We are looking for postdoc candidates with experience in epigenetics, transcription, RNA, or single cell biology.  Experience working with developmental biology models, organoids or mice is a plus.  No prior experience in microscopy is necessary.

To Apply:

Interested candidates should send a short statement of how their interests and research accomplishments fit with interests in the lab, CV and contact information for 3 references to

Joseph Rodriguez, PhD
Single Cell Dynamics Group
Epigenetics and Stem Cell Biology Laboratory
National Institute of Environmental Health Sciences, NIH
Research Triangle Park, North Carolina

Application Deadline Date: November 1, 2020


This post will be available until November 1, 2020 or until filled.

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