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Role of Sterol Metabolism in Host Response to Virus

National Institute of Environmental Health Sciences, Research Triangle Park, NC

Position Description:   

A postdoctoral fellow with expertise in virology is sought for studies of the role of cholesterol metabolism in the host cellular response to virus.  The primary focus will be on Coronaviridae and will include therapeutic strategies potentially applicable to SARS-CoV-2 that are under active study in the laboratory.  Studies will utilize epithelial cell culture (primary and cell lines) and may also employ organoids and mouse models. 

This position is in the Host Defense Group of the Immunity, Inflammation and Disease Laboratory (IIDL), a Branch within the intramural research program of the NIEHS, located in Research Triangle Park, NC.   The NIEHS has extensive core facilities, including cores in bioinformatics, genomics, bioinformatics, flow cytometry, proteomics, metabolomics, imaging, viral vectors, protein expression, and transgenic mouse production that together offer the trainee wide latitude in the design and pursuit of their research questions.


Applicants must be very close to obtaining, or have a Ph.D. and/or M.D., ideally with less than 5 years of postdoctoral training.  Expertise in sterol metabolism is not essential, whereas a solid background in virus-centered assays and related cell/molecular biology is strongly desired.

To Apply:  

For immediate consideration,  applicants should send the following materials to Dr. Michael Fessler, Senior Investigator, IIDL/NIEHS ( (i) a Curriculum Vitae (C.V.) including education/training history and bibliography; and (ii) a list of at least 3 references with email addresses and phone numbers.

Any questions relating to the position can be directed to Dr. Fessler at the email address listed above.


This post will be available until October 17, 2020 or until filled.

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