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Acute Pain and Inflammation in Sickle Cell Disease

National Heart, Lung, and Blood Institute, Bethesda, MD and surrounding area

Position Description:

A clinical researcher position is available in Dr. Swee Lay Thein’s laboratory (Laboratory of Sickle Cell Genetics and Pathophysiology) in the Sickle Cell Branch of the National Heart, Lung, and Blood Institute, NIH. The laboratory is interested in the study of genetic modifiers and pathophysiology in sickle cell disease (SCD). Specifically, the post-doctoral fellow’s research will utilize a combination of molecular biology, flow cytometry, and tissue culturing techniques, as well as animal (mouse and porcine) studies in identifying the mechanisms associated with, as well as biomarkers that will allow monitoring of acute pain and inflammation in SCD. This position will also explore the use of an investigational drug as a modifier of sickle cell severity in sickle cell mice. More information on the laboratory is available at https://www.nhlbi.nih.gov/science/sickle-cell-genetics-and-pathophysiology.

The successful applicant will have Doctor of Medicine (MD) and/or Doctor of Philosophy (PhD), experience in the related field (Sickle Cell Research) and experience in clinical research. S/he will have strong communication, organizational, and time management skills, detail oriented, and with an ability to work independently as well as collaborate as a team member. The successful candidate will have the opportunity to utilize an interdisciplinary approach to pursue research interests and advance to an independent research career in the NIH intramural program, which includes supportive and advanced core facilities specializing in transgenic mice, human iPS cells, advanced microscopy, sequencing, proteomics, biochemistry and bioinformatics.

Qualifications:

Candidates must have obtained a Ph.D. or M.D. degree  with background in clinical research and the related field. The ideal candidate should have a strong background in either genetics/genomics, immunology or molecular biology, as demonstrated by first-author publications in peer reviewed journals.

Salary/Benefits:

This position is fully supported by NIH intramural funds and successful candidates will be offered competitive stipend/health insurance commensurate with experience and accomplishments.

To Apply:

Applications from women, minorities and persons with disabilities are strongly encouraged. Applicants should send their curriculum vitae and a brief statement of research interests/career goals, and request 3 letters of reference to be sent via email to: sweelay.thein@nih.gov.

 

This post will be available until May 18, 2021 or until filled.

The NIH is dedicated to building a diverse community in its training and employment programs.

HHS and NIH are Equal Opportunity Employers.