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Immunological Aspects of Viral Infections in Patients with Mitochondrial Diseases

National Human Genome Research Institute, Bethesda, MD and surrounding area

Position Description:

Viral infection is a leading cause of significant morbidity and mortality in patients with mitochondrial disease. The Metabolism, Infection and Immunity Section (MINI Section) of NHGRI takes a translational approach to understanding host-pathogen interactions in children with mitochondrial disease. The project for this position is focused on defining the mechanisms of viral pathophysiology and antiviral immune responses in children with mitochondrial disease. In addition to immunology and molecular biology studies, the successful candidate will employ innovative approaches including: patient studies, iPS cells, animal models, genomics, metabolomics, stable isotope flux, and bioenergetics studies.


We are seeking a highly motivated, creative and collaborative individual with a publication record, who is able to engage in independent reasoning and excited about integrating molecular biology, immunology and omic technologies to understand mechanisms of pathophysiology. Ideal candidates must have a Ph.D. and/or M.D. and < 5 years of postdoctoral training. Preference will be given to candidates who have a background in immunology and strong knowledge of molecular biology.  Prior experience with  metabolism and viral pathophysiology is a plus. The candidate should have excellent writing and communication skills.

To Apply:

If you are interested, please send a research statement, curriculum vitae, and the names

and contact information of 3 references to:

Peter J. McGuire MS, MD
Metabolism, Infection and Immunity Section
National Human Genome Research Institute
National Institutes of Health
10 Center Drive
Room 7N260A
Bethesda, MD 20892
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