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Gene Regulation in the Immune System

National Eye Institute, Bethesda, MD and surrounding area

Position Description:

Postdoctoral positions are available in the laboratory of Dr. Han-Yu Shih at the National Institutes of Health (NIH) in Bethesda, MD. Our lab aims to understand multi-dimensional gene regulation during immune cell differentiation and activation in health and immunological diseases. The candidates will investigate the transcriptomes and epigenomes in primary immune cells from infectious, autoimmune or neurodegenerative mouse models. The ultimate goal is to identify novel transcriptional networks and molecular mechanisms as potential therapeutic targets. 
This position offers exposure to multidisciplinary and cutting-edge genomic research and opportunities to collaborate closely with experts in immunology, neurobiology and bioinformatics. The candidates will be leading/co-leading projects, designing experiments for generating high-dimensional data while working closely with collaborators and lab members. Candidates from wet and/or dry benches are welcome.


  • Candidates must hold a Ph.D. or M.D./Ph.D. in immunology, neuroscience, genetics, molecular biology, biochemistry or a related field, within three years of degree being awarded;
  • Must have first authorship on at least one peer-reviewed publication;
  • Must be self-motivated and keen to develop and/or learn cutting-edge technologies and/or up-to-date genomic data analysis;
  • The ability to work as part of a cohesive group is important as we are a highly collaborative lab;
  • Have excellent writing and communication skills. 

To Apply:

Interested candidates please send a cover letter, curriculum vitae, and contact information of three references to:

NEI Shih Lab

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