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Glia-Neuron Interactions

National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD and surrounding area

Position description:

Two postdoctoral positions are available (open until filled) to work in the field of glial biology in the laboratory of Dr. Ashley Frakes. In the Frakes lab, we leverage the versatility of multiple model systems (C. elegans, cell culture, and mice) to reveal the mechanisms glial cells employ to coordinate metabolic homeostasis within the central nervous system and peripheral tissues. We use a combination of tools including genetics, microscopy, animal behavioral assays, viral transduction, and single-cell functional genomics. Our long-term goal is to identify the fundamental cellular mechanisms that drive aging and give rise to age-onset metabolic and neurodegenerative diseases.


Candidates must hold a doctoral degree (PhD, MD, DDS or the equivalent) in molecular and cell biology, neuroscience or related fields. Candidates with a wide range of expertise will be considered. Those with experience working with transgenic mouse models, C. elegans, single cell genomics, or studying cellular communication and signaling are highly encouraged to apply.  Candidates must possess strong oral and written communication skills, excellent organizational and recordkeeping skills, and have the ability to work independently as well as collaboratively with others.

To Apply:

Interested individuals should submit their CV, a cover letter outlining interests and accomplishments, and three letters of reference, to Liz Perry (
Please indicate in your cover letter why you are interested in joining the Frakes lab. All qualified individuals are encouraged to apply.
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