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Calcium Signaling & Regulation of Cell Function

National Institute of Dental & Craniofacial Research, Bethesda, MD and surrounding area

Position Description:

Postdoctoral position is currently available in the Secretory Physiology Section, NIDCR, NIH, to study the molecular mechanisms underlying calcium signaling, with a specific focus on the assembly of STIM/Orai channel complex.  The current project aims to identify and characterize the molecular components that regulate STIM protein clustering in the ER-plasma membrane junctions. We use a variety of molecular and imaging approaches, together with genetic manipulation of cells and molecular simulation of STIM protein dynamics.  There will also be an opportunity to work on a second project that examines the role of oxidative stress on cellular Ca2+ signaling mechanisms and their contribution to disease and dysfunction. 
 

Qualifications:

Applicants should have a Ph.D. with less than 3 years of postdoctoral experience, good oral and written communication skills and a strong background in physiology and biochemistry. Expertise in cellular imaging, molecular biology, and various biochemistry techniques are required. Additional experience in calcium signaling and working with animal models.
 

To Apply:

Applicants should send details of research experience and technical expertise, together with a complete CV and the names and contact information of three references to Dr. Indu Ambudkar (indu.ambudkar@nih.gov).
 
The lab is situated on the main campus of NIH in Bethesda, MD, and offers a highly collaborative, multi-cultural, training environment for young scientists with cutting-edge resources and expertise.
 
The salary and benefits are as per NIH regulations commensurate with experience
 
 

The NIH and HHS are dedicated to building a diverse community in their training and employment programs.