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Genetics of Primary Immunodeficiencies

National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD and surrounding area

The National Institute of Allergy and Infectious Diseases (NIAID) conducts and supports a global program of research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. The Laboratory of Clinical Immunology and Microbiology (LCIM) within the NIAID Division of Intramural Research (DIR) is seeking candidates for a postdoctoral fellow position within the Immune Deficiency Genetics Section (IDGS). Research at IDGS is mainly focused on defining the molecular and cellular bases of novel forms of human inborn errors of immunity; understanding the mechanisms underlying manifestations of immune dysregulation in patients with various forms of combined immune deficiency; and developing novel approaches to correct these disorders. The candidate will be mainly involved in modeling tissue-specific effects caused by mutations in genes associated with inborn errors of immunity by using targeted differentiation of induced pluripotent stem cells (iPSCs) and gene editing technologies.


  • PhD in immunology, cell biology, or related discipline
  • A record of relevant, high-quality publications
  • Excellent project management and organizational skills
  • Collaborative attitude

Preferred Qualifications

  • Experience with generation, maintenance, and targeted differentiation of iPSCs, developmental biology, gene editing, molecular biology, and flow cytometry
  • Experience with bioinformatics (such as R/Python)

To Apply

Interested candidates should send their curriculum vitae (CV), bibliography, three references who may be contacted for letters, and a short statement about their skill set and research interests (no more than two pages) to Dr. Luigi D. Notarangelo at

Additional Information

  • As a condition of employment, all federal employees must be fully vaccinated against COVID-19. During the on-boarding process, if selected, you must provide proof of vaccination. An official job offer and continued employment are contingent on meeting this requirement. For more information on this requirement, visit the Safer Federal Workforce page on vaccines. If you need a COVID-19 vaccine, please visit
  • Due to COVID-19, we are currently operating in a maximum telework state. If selected, you may be expected to telework. As employees to return to the office, you may be required to report to the location listed on this announcement within 30 calendar days of receiving notice, even if your home/temporary telework site is located outside the local commuting area. At the discretion of the supervisor and NIH policy, you may be eligible for workplace flexibilities, which may include remote work or telework options, and/or flexible work scheduling. These flexibilities may be requested in accordance with NIH Workplace Flexibilities guidance.

Visit NIAID Careers for more information about working in NIAID’s dynamic atmosphere.

This position is subject to a background investigation.
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