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Leukemia Genetics: In Vivo and In Vitro Models

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:

A postdoctoral fellow position is available in the laboratory of Dr. Peter Aplan, Genetics Branch, NCI/NIH to study in vitro and in vivo models of hematologic malignancy, especially acute leukemias. Dr. Aplan's lab has generated mouse models for myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) as well as B- and T-cell acute lymphoblastic leukemia (ALL), using molecular genetic and gene editing techniques. The successful candidate will investigate the mechanisms by which these models lead to hematologic malignancy, including the acquisition of somatic mutations, as well as learn to use these models as pre-clinical platforms for development of small molecule, protein and cell based therapies. To learn more about current research, please visit:


Qualified candidates must have an M.D., Ph.D. or equivalent degree in a relevant field. Candidates with experience in mouse models, hematopoietic differentiation, and next generation sequencing approaches are encouraged to apply.

To Apply:

Applications, including curriculum vitae and personal statement, should be sent to:
Peter D. Aplan MD
Senior Investigator and
Head, Leukemia Biology Section
Genetics Branch
37 Convent Drive Room 6002
Bethesda, MD 20892

The NIH is dedicated to building a diverse community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.