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Georgetown University - Biomedical Sciences: University Professors

Professor Department Research Interests
Ahern, Gerard, Ph.D. Pharmacology Molecular sensory biology; Pain receptors, electrophysiology
Albanese, Chris, Ph.D. Oncology Role of oncogenes, tumor supressor proteins and cyclin D1 in initiation and progression of prostate and breast cancers
Anita Sidhu, Ph.D. Biochemistry and Molecular & Cellular Biology Role of synucleins in neurodegenerative diseases [Parkinsonson's and Alzheimer's disease] and depression, and modulation of monoamine transporters, and cancer. Development of novel therapies against these diseases using cell and animal models.
Avantaggiati, Maria Laura M.D., Ph.D. Oncology Role of the p53 tumor suppressor and of deacetylases in metabolic pathways that confer cancer protection
Banerjee, Partha, Ph.D. Biochemistry and Molecular & Cellular Biology Epigenetic silencing of tumor suppressor genes; plant alkaloids and phytoestrogens as therapeutics; extra-telomeric roles of telomerase
Brown, Milton, M.D., Ph.D. Oncology (Neuroscience) Anti-cancer drug discovery and the role of voltage gated sodium channels in the etiology and progression of prostate cancer
TBD Pharmacology New drug discovery, genetics
Byers, Steve, Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology) Gene environment interactions focused on vitamins A and D and Wnt signaling in breast and colorectal cancer
Casey , John, Ph.D. Microbiology Hepatitis B and C virus
Chang, Esther, Ph.D. Oncology (Otolaryngology) Tumor-targeting nanodelivery platform for the improvement of cancer therapy and diagnosis
Chung, Fung-Lung, Ph.D. Oncology Chemical cardinogenesis and DNA damage by environmental and endogenous chemicals and mechanism-based chemopreventive agents
Clarke, Robert, Ph.D., D.Sc. Oncology Studies hormones (endo- and exogenous) and related factors affect breast cancer, and how breast cancers become resistant to endocrine and cytotoxic chemotherapies
Cote , Paul, Ph.D. Microbiology Hepatitis B and C virus
Crooke, Elliott, Ph.D. Biochemistry and Molecular & Cellular Biology Control of chromosomal replication; role of polyphosphates in cellular responses to environmental stresses
Danielsen, Mark, Ph.D. Biochemistry and Molecular & Cellular Biology Detection of pathogenic organisms for medical diagnosis and bioterrorism surveillance. Nuclear receptors. Thyroid (Graves disease and thyroid cancer).
Deeken, John, M.D. Cancer Center Pharmacogenetic evaluation of high-throughput platforms; Systems-level investigations of organogenesis
Djakiew, Daniel, Ph.D. Biochemistry and Molecular & Cellular Biology Role of p75NTR in cancer and nervous system. Drug induced up-regulation of p75NTR to inhibit tumor growth. Drug induced down-regulation of p75NTR to promote neuronal cell survival.
Dym, Martin, Ph.D. Biochemistry and Molecular & Cellular Biology Male germ line stem cells; role of miRNAs; Signaling; reprogramming to iPS cells; isolation, characterization and culture of human spermatogonial stem cells
Edwards, Nathan, Ph.D. Biochemistry and Molecular & Cellular Biology Mass spectrometry, proteomics, and glycomics informatics; ultra-specific oligonucleotide assay design
Fornace, Albert, M.D. Biochemistry and Molecular & Cellular Biology (Oncology) Oncogenic and genotoxic stress signaling, including application of systems biology approaches to stress signaling in cancer; Cell signaling in immune cells; Oncogenic and genotoxic stress signaling, including application of systems biology approaches to stress signaling in cancer
Furth, Priscilla A., M.D. Oncology (Medicine) Breast Cancer Pathophysiology and role of hormone signaling pathways; cancer virus pathophysiology; preneoplasia reversal; and chemoprevention
Gallicano, Ian, Ph.D. Biochemistry and Molecular & Cellular Biology Identifying mechanisms regulating stem cell pluripotency and differenetion into specific celluar lineages for eventual use in stem cell therapies.
Gilis, Richard, Ph.D. Pharmacology CNS control of GI and cardiovascular function
Glazer, Robert, Ph.D. Pharmacology Kinase regulation of tumor growth and multidrug resistance
TBD Oncology (Pharmacology) PDK1 in mammary epithelial cell transformation and metastasis; PPAR-gamma in chemoprevention and stem cell self-renewal
Goldman, Radoslav, Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology) Studies of progression of chronic hepatitis viral infection to hepatocellular carcinoma, identification of markers for early detection of cancer
Hilakivi-Clarke, Leena, Ph.D. Oncology Gene and nutrition/obesity interactions in the prevention of breast and other endocrine cancers; stress and breast cancer
Hurley, Carolyn Katovich, Ph.D., D (ABHI) Oncology (Microbiology and Immunology) Impact of genetic diversity on human immune response
Johnson, Michael, Ph.D. Oncology Role of proteases in the invasion, progression, and metastasis of breast cancer; Survival signaling in Myc-driven mammary carcinogenesis
Jones, Jessica, Ph.D. Biochemistry and Molecular & Cellular Biology Role of RAG1 ubiquitin ligase activity and KPNA1 in V(D)J recombination and B and T cell development.
Jordan, V. Craig, Ph.D., D.Sc. Oncology Endocrine resistance in breast cancer
Kasid, Usha, Ph.D. Radiation Medicine (Biochemistry and Molecular & Cellular Biology) Raf-1/Erk signaling; signal transduction mechanisms of tumor growth, metastasis, and radiation and chemoresistance.
Kellar, Kenneth, Ph.D. Pharmacology brain nicotinic receptors, antidepressant mechanisms
Korba, Brent, Ph.D. Microbiology Hepatitis B and C virus
Loffredo, Christopher, Ph.D. Oncology (Biostatistics, Biomathematics & Bioinformatics) Role of infectious diseases, environmental exposures, and genetic susceptibility to cancers of childhood and adulthood
Maguire-Zeiss, Kathy, Ph.D. Pharmacology Neurodegenerative disease
Martin, Mary Beth, Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology) Role of estrogen and the estrogen receptor in etiology and progression of breast cancer
McGarvey, Peter, Ph.D. Biochemistry and Molecular & Cellular Biology Bioinformatics, genomic and proteomic analysis, biological databases and data visualization.
Mocchetti, Italo, Ph.D. Pharmacology Neurotrophins and disease
Mueller, Susette, Ph.D. Oncology Role of tyrosine kinases in regulating breast cancer cell invasion and role of invadopodia
Nakai, Hiroshi, Ph.D. Biochemistry and Molecular & Cellular Biology Mechanism of linking recombination and replication in transposition and replication restart pathways; role of molecular chaperones in chromatin remodeling and regulated proteolysis
Notario, Vicente, Ph.D. Radiation Medicine (Biochemistry and Molecular & Cellular Biology: Oncology) Role of oncogenes in mechanisms of human carcinogenesis and cellular stress response, with emphasis on molecular targets and pathways for chemo- and radiosensitization
Padmanabhan , Pad, Ph.D. Microbiology West Nile/Dengue virus
Pak, Daniel, Ph.D. Pharmacology Molecular synaptic plasticity
Rebeck, G. William, Ph.D. Pharmacology Neurodegenerative disease
Riegel, Anna, Ph.D. Pharmacology Transcriptional regulation
TBD Oncology (Pharmacology) Mechanisms of cross talk between hormone and growth factor signaling in human breast and pancreatic cancer
Roepe, Paul Ph.D. Chemistry (Biochemistry and Molecular & Cellular Biology) Drug resistance in infectious diseases and cancer.  Drug design and discovery, including natural products screens.  Cell imaging techniques as applied to physiology of drug resistant cells and microbes.
Rosen, Eliot, M.D., Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology; Radiation Medicine) Role of BRCA1 in estrogen receptor signaling, tumor suppression, and chemoprevention in breast cancer; mechanisms of scatter factor/c-Met mediated protection against apoptosis and implications for overcoming chemoresistance in breast and prostate carcinomas
Rosenthal, Dean, Ph.D. Biochemistry and Molecular & Cellular Biology The role of Id proteins in apoptosis, differentiation and tumorigenesis in skin cells.  We are using a human skin graft system to monitor the fate of primary fibroblasts, keratinocytes, and melanocytes following modulation of expression of Id proteins and other related proteins to study human epithelial carcinogenesis in vivo.  This will allow us to develop diagnostic and therapeutic reagents for the treatment of carcinomas, melanomas, and other skin diseases.
Roy, Rabindra, Ph.D. Oncology Role of repair mechanisms of oxidative and alkylation DNA damage in mutations, cancer and chemoprevention
Schlegel, C. Richard, M.D., Ph.D. Pathology (Oncology; Microbiology and Immunology, ObGyn) Molecular and immunological studies of the human papillomaviruses and their role in neoplasia
Seillier-Moiseiwitsch, Francoise, Ph.D. Biostatistics, Bioinformatics, & Biomathematics (Oncology Develop statistical methods for genomics and proteomics. Investigate statistical methodology for analysis of molecular genetic data, 2D gels and protein profiles related to cancer progression
Shields, Peter, M.D. Oncology (Medicine) Molecular epidemiology and carcinogenesis for breast and lung cancer
Smulson, Mark, Ph.D. Biochemistry and Molecular & Cellular Biology Effects of poly( ADP-ribosylation) on chromatin structure and function
Suarez-Quian, Carlos, Ph.D. Biochemistry and Molecular & Cellular Biology Gross anatomy medical education using electronic media as a supplement.
Suzuki, Justin, Ph.D. Pharmacology Vitamin C: pulmonary hypertension/asthma
Tang, Careen K., Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology)
Role of ErbB receptors and CXCR4 in human cancer progression and metastasis to cadaveric dissection.
Toretsky, Jeffrey, M.D. Oncology (Pediatrics and Medicine) Development of novel childhood cancer therapeutics using chemical genomics
Turner, R. Scott, Ph.D. Pharmacology Alzheimer's: phospholipids
Uren, Aykut, M.D. Oncology (Biochemistry and Molecular & Cellular Biology) Role of Wnt-beta-catenin signaling in tumor pathogenesis.  Molecular mechanisms of transformation and metastasis in pediatric sarcomas
Vicini, Stefano, Ph.D. Pharmacology Synaptic transmission
Waldman, Todd, M.D., Ph.D. Oncology (Biochemistry and Molecular & Cellular Biology; Pharmacology) Functional analysis of the PTEN tumor suppressor gene and genetic analysis of glioblastoma pathogenesis
Weiner, Louis, M.D. Oncology immunotherapy and gastrointestinal cancer, with an emphasis on monoclonal antibody engineering and antibody-based therapy
Wellstein, Anton, M.D., Ph.D. Oncology (Pharmacology, Medicine) Role of growth factors in the cancer cell/stroma interaction
Wu, Cathy, Ph.D. Biochemistry and Molecular & Cellular Biology Computational Systems Biology--Omics Data Integration and Pathway/Network Analysis; Structure/Function Relationship; Biological Text Mining and Bioinformatics Cyber infrastructure
Zhang-Zhi Hu, M.D. Oncology (Biochemistry and Molecular & Cellular Biology) Cancer systems biology: estrogen singaling pathway and network modeling in breast cancer; protein O-GlcNAcylation network in cancer cell signaling and epigenetic regulation; Melanosome biogenesis pathway and melanoma; Tumor immunology and the design of antiviral drugs against HIV

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