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Reproducibility of Data Collection and Analysis

Modern Technologies in Genome Technology: Potentials and Pitfalls
Thursday, June 4, 2015 from 12:30pm - 5:00pm
Building 45 / Room E-1/E-2

This is the third of three workshops sponsored by the NIH Office of the Director on the important topic of reproducibility, the subject of recent editorials in leading scientific journals.

The purpose of these workshops is to educate the NIH intramural research community about what advanced technologies can accomplish and the kinds of reproducibility problems that can arise; provide a cautionary note to scientists who hope to use but are inexperienced with various new modeling techniques; and educate others who are attempting to interpret results in the literature.

We have invited several world-class scientists who will speak about important technologies in genome technology. In addition, we have invited editors from scientific journals covering structural biology to moderate sessions and discuss issues with data reproducibility in the scientific literature. We encourage you to mark this event on your calendar, and we hope you will be able to attend, either in person or through the videocast at (available the day of the event).

We welcome our colleagues beyond the NIH to watch the videocast, too, which also will be archived. If you have any questions, please e-mail Dr. Paul Liu at


Michael Gottesman, M.D.
Deputy Director for Intramural Research
National Institutes of Health


12:30pm: Opening Remarks
Eric Green (Director, NHGRI)

12:40pm: Session 1: Genomics in Clinical Research
David Nelson, PhD (American Journal of Human Genetics; Moderator)
Stephen Chanock (NCI)
Les Biesecker (NHGRI)

1:40pm: Session 2: Whole Genome and Exome Sequencing
Hillary Sussman, PhD (Genome Research; Moderator)
James Mullikin, PhD (NHGRI; Speaker)
James Taylor, PhD (Johns Hopkins University; Speaker)

2:40pm: Break

3:00pm: Session 3: ChIP-Seq and other Epigenomic Tools
Kyle Vogan, PhD (Nature Genetics; Moderator)
Keji Zhao, PhD (NHLBI; Speaker)
Shirley Liu, PhD (Harvard University; Speaker)

4:00pm: Session 4: RNA-Seq
Natalie de Souza, PhD (Nature Methods; Moderator)
Paul Meltzer, MD, PhD (NCI; Speaker)
Christopher Mason, PhD (Cornell University; Speaker)

5:00pm: Closing Remarks
Stephen Chanock, MD (NCI)