Postdoctoral Fellow (NCI)

Our lab studies the function of mammalian polo-like kinase 4 and 1 (Plk4 and Plk1), which play central roles in regulating various biological events, including centriole duplication, bipolar spindle formation, chromosome segregation, cell division, and proliferation. Dysregulation of Plk4/Plk1-dependent processes, by mutations in their associated cellular components or by HIV accessory proteins, is tightly linked to the development of aneuploidy and cancer.

During the past several years, we have been using biochemical, biophysical, and structural approaches, including super-resolution imaging, single-molecule tracking, in vitro reconstitution, X-ray crystallography, and cryo-EM, to delineate the molecular basis and structural rules governing the architecture and function of centrosomes, as their deregulation can lead to the development of various cancers, microcephaly, and AIDS.

Please visit here to read more about our lab and explore our publications.

This position starts at $68,544 for those with no years of prior postdoc training and includes complete health insurance and annual raises.

Prospective fellows with expertise in the biochemical and biophysical characterization of regulatory proteins and their structural determination, specifically using X-ray crystallography and/or cryo-EM, are strongly preferred. Those with a strong interest in understanding the organization and function of centrosomes and their relevance to pathophysiological disorders, including cancer and AIDS, are strongly encouraged to apply.

All applicants should have a Ph.D., M.D., or equivalent degree received in the last three years (or expect to receive one shortly).

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs. U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.