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Job

Postdoctoral Fellow

Organization

National Institute of Child Health & Human Development, Bethesda, MD and surrounding area

Scientific focus area

Neuroscience, Stem Cell Biology, Chromosome Biology, Developmental Biology, Genetics and Genomics, Molecular Biology and Biochemistry

The Section on Cellular and Molecular Neurodevelopment at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), in Bethesda MD is seeking an enthusiastic and highly motivated postdoctoral candidate to join our laboratory studying neurodevelopment.

About the position

GABAergic inhibitory interneurons are an extremely heterogeneous cell population with distinct morphologies, connectivity, neurochemical markers, electrophysiological properties and transcriptomes. Abnormal development and function of interneurons has been linked to the pathobiology of numerous brain diseases such as epilepsy, schizophrenia and autism. Recent studies have found that many disease-associated genes are expressed in immature interneurons. Thus, a thorough description of the genetic and epigenetic mechanisms regulating interneuron fate and maturation is critical to understand both normal development and disease models.

To this end, our lab utilizes cutting-edge techniques to characterize the genetic, epigenetic and environmental mechanisms in the embryonic forebrain that regulate the diversity and maturation of interneurons. These approaches include (but are not limited to) single cell sequencing technologies, spatial transcriptomics, stem cell differentiations, in utero electroporation, cell transplantations and numerous other techniques to manipulate gene expression.

For more information about the scientific questions we explore, ongoing projects, our team and publications, please visit the lab website: https://www.nichd.nih.gov/research/atNICHD/Investigators/petros

Apply for this vacancy

What you'll need to apply

Interested applicants should submit their CV and a statement of research interests to [email protected].

Contact name

Timothy Petros

Contact email

[email protected]

Qualifications

Skills and Qualifications:

  • Ph.D. and/or M.D. in neuroscience, developmental biology, cell biology, genetics or related discipline
  • Strong work ethic and ability to design, carry out and analyze independent projects that encompass the overall theme of the lab
  • Candidates with significant experience involving single cell sequencing, brain organoids and/or human iPSC differentiations are strongly encouraged to apply

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