Postdoctoral Associate (Connecticut)

The successful candidate will have the opportunity to work on cutting-edge research projects establishing an in vitro gastrointestinal host immune-microbiome culture model for disease modeling and therapeutic development.This project involves multiple technologies, including organoid engineering, organ-on-a-chip platforms, microfluidics, and microbiome science, for modeling intestinal inflammatory conditions, such as Crohn’s disease, ulcerative colitis, celiac disease, and eosinophilic esophagitis.

We will also use mouse- and patient-derived cells/organoids and microbiomes, in concert with our complex Organ Chip models, to study the underlying mechanisms of these diseases and the role of immune cells in regulating and responding to intestinal microbiota. The prospective postdoctoral scientist will help lead this exciting project applying a broad range of cutting-edge technologies, such as Organ-on-a-Chip development, organoid culture, microbiome sequencing, single-cell transcriptomics, metagenomics and proteomics.

This position also leverages collaboration between clinicians and investigators at the Jackson Laboratory, Connecticut Children’s, and UConn Health. The ideal candidate should have a strong background in biomedical engineering, organoid culture, and immunology. Prior research experience in gastroenterology is preferred.

Applicants must have a Ph.D. in biomedical sciences, bioengineering, microbiology, immunology or a related field of study. Strong skillsets in cell and tissue engineering and a training background in bioengineering, immunoengineering and cell biology is also highly desirable. Experience with in-vivo models, gastroenterology research, bacterial cultures, host-microbiome interactions, and multi-omics approaches is particularly preferred.

Candidates should also have at least one 1st author publication record in peer-reviewed journal, excellent writing and communication skills, and the able to work both independently and as part of a productive team.

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.