Postdoctoral Fellow (FDA)

The Center for Biologics Evaluation and Researches mission is to protect and enhance public health through the regulation of biological and related products, including blood, vaccines, allergenics, tissues, and cellular and gene therapies. As a postdoctoral fellow in our lab, your research project will focus on advancing the development and manufacturing of CRISPR/Cas9-edited hematopoietic stem cell therapeutics. Prospective fellows will gain experience in cutting-edge genome editing techniques as they are applied to human hematopoietic stem cell therapeutics and related cell types.

Our lab operates at the intersection of stem cell biology, gene therapy, and nanomedicine, addressing one of the most significant challenges in our field: the achievement of safe and effective delivery of gene-editing machinery to hematopoietic stem cells. Fellows will utilize state-of-the-art manufacturing tools and methodologies to investigate and optimize ex vivo HSC-gene editing and expansion protocols. They will gain comprehensive training in the design, development, and optimization of novel lipid nanoparticle formulations specifically engineered for efficient gene editing.

This training opportunity is ideal for individuals seeking to contribute to the advancement of non-viral delivery platforms that could transform the landscape of HSC-based gene therapies and cellular therapeutics.

Qualified candidates should have received or be pursuing a Ph.D., or equivalent degree, in molecular and cell biology, pharmacology and drug discovery or development. Preferably, candidates will have postdoctoral experience in CRISPR gene editing, molecular biology, cell biology and/or immunology. Expertise in stem cell biology, genome editing, non-viral gene delivery systems, lipid nanoparticle, and high throughput sequencing is highly desirable.

If your education was completed at foreign colleges or universities, you must show that your education credentials have been evaluated by a private organization specializing in interpretation of foreign education programs, and that such education has been deemed equivalent to that gained at an accredited U.S. education program, or that full credit has been given for your coursework by an U.S. accredited college or university.

HHS/FDA is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. U.S. citizens and permanent residents are eligible to apply. FDA welcomes foreign nationals with the exception of individuals from this list.