Job
Postdoctoral Fellow: Translational Neuroimmunology & Human Cerebral Organoids
Organization
National Institute of Allergy and Infectious Diseases, Bethesda, MD and surrounding area
Scientific focus area
Neuroscience, Immunology
Join a multidisciplinary team dedicated to identifying druggable mechanisms of CNS tissue destruction and repair. We bridge the gap between clinical observation and molecular mechanism by investigating neural-immune interactions in myelinated human cerebral organoids.
About the position
The Science: You will leverage our extensive library of proteomic and transcriptomic data derived from the cerebrospinal fluid (CSF) of patients with neuroimmunological diseases. Having identified likely causal pathways of injury and resilience, we are now validating these mechanisms using:
- Human Models: Cerebral organoids derived from iPSCs of human subjects with defined genotypes.
- Complex Systems: Co-cultures with autologous immune cells to model sterile or infection-associated inflammation.
- Advanced Omics: Genomic and therapeutic manipulation of pathways analyzed via multiplex spatial profiling, CITE-seq, and multiplex proteomics.
The Impact: This position offers rigorous training in independent, highly reproducible translational research. Your work will directly contribute to developing therapies that strengthen the health and wellbeing of people with neuroimmunological diseases.
Apply for this vacancy
What you'll need to apply
To Apply Interested candidates should send the following:
- Curriculum vitae
- Bibliography
- Contact information for three references
- A short statement (max 2 pages) detailing your skill set and research interests
Contact name
Bibiana Bielekova
Contact email
Qualifications
- Education: Ph.D. or M.D. in Immunology, Neuroscience, Cell Biology, or related discipline.
- Required Skills: Extensive tissue culture experience; molecular biology/gene editing (CRISPR/Cas9); a record of high-quality publications.
- Preferred Skills: Flow cytometry, fluorescence microscopy, bioinformatics (R/Python/MATLAB).
- Mindset: A strong interest in multidisciplinary research and neuroimmune interactions.
Disclaimer/Fine Print
U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.
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