Postdoctoral Fellow - Tumor virus RNA biology of virus infection and tumorigenesis

Postdoctoral fellow will perform basic research on DNA tumor viruses (papillomavirus and Kaposi’s sarcoma-associated herpesvirus). This includes studies on genome structure, integration and expression, RNA splicing and post-transcriptional regulation of viral and host RNA transcripts, noncoding RNAs and nonsense-mediated RNA decay, and protein-RNA and RNA-RNA interactions in virus infection and tumorigenesis. Our overall goal is to understand how DNA tumor viruses interact with host factors in infected cells to express their essential genes at transcriptional and post-transcriptional levels. We aim to further understand how these viruses are responsible for disrupting the host cell functions, promoting cell transformation and clonal expansion. We use high-throughput technologies, various high-resolution imaging techniques, in vivo and in vitro RNA processing assays, gene knockouts and rescue experiments in mammalian cells, and transgenic animal models to gain new insights into the mechanisms and dynamics of DNA tumor virus molecular biology.

Applicants must have a strong background in molecular virology, molecular biology, biochemistry, and/or RNA biology. Interested candidates must have a Ph.D. and/or an M.D. and have less than 5 years of relevant postdoctoral experience

U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.