Postdoctoral Position on immunology of tonsil disorders

We are seeking a highly motivated researcher to join our team in studying the mechanism of human inflammatory tonsil disorders, including a periodic fever syndrome called PFAPA (periodic fever, aphthous stomatitis, pharyngitis, adenitis), recurrent tonsillitis, and obstructive sleep apnea in children. Although these conditions are common, their causes and underlying immunological mechanisms are not well-characterized. Our unit’s preliminary data suggest unique immunologic features in the tonsils of patients in each of these conditions, and our lab aims to further understand the immunopathogenic mechanisms. The successful candidate will use advanced techniques in immunology such as spectral flow cytometry, cell culture and functional studies, single-cell RNA sequencing, spatial transcriptomics, and multiplexed imaging. The candidate will be responsible for leading innovative research projects including performing experiments at the bench, analyzing and interpreting data, preparing manuscripts for publication in high-impact journals, and presenting findings at national and international conferences. Additionally, the role involves mentoring and training junior lab members. This is an excellent opportunity for a dedicated researcher to advance their career in a dynamic and supportive environment and work with a multidisciplinary team of clinicians and basic scientists and perform translational research on human samples. Please see Dr. Kalpana Manthiram’s research page for more information.

Highly motivated candidates with an M.D. and/or Ph.D in biomedical genetics, bioinformatics, biostatistics, or genetic epidemiology or related fields are encouraged to apply. Experience analyzing large complex genetic datasets is an advantage. The successful candidate will have demonstrated the ability to conduct independent research and possess a track record of scientific publications with the ability to work effectively in a collaborative team environment and well-developed oral and written communication skills.

U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.